Dietitian-led lifestyle modification programme for obese Chinese adolescents with non-alcoholic fatty liver disease: a randomized controlled study
| Autor: | Edmund A S Nelson, Madelynn Chan, Steve C. N. Hui, Winnie C.W. Chu, Ruth Chan, H. K. So, Dorothy F.Y. Chan, Jean Woo, Mandy Man-Mei Sea, Albert M. Li |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty China Multivariate analysis Adolescent Endocrinology Diabetes and Metabolism Prevalence Medicine (miscellaneous) Disease Health Promotion law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Lifestyle modification law Non-alcoholic Fatty Liver Disease Internal medicine medicine Humans 030212 general & internal medicine Nutritionists Life Style Triglycerides Nutrition and Dietetics business.industry Fatty liver medicine.disease Obesity Liver 030211 gastroenterology & hepatology Female business Body mass index |
| Zdroj: | International journal of obesity (2005). 42(9) |
| ISSN: | 1476-5497 |
| Popis: | The prevalence of non-alcoholic fatty liver disease (NAFLD) in children is increasing. This study evaluated the efficacy of a dietitian-led lifestyle modification programme (D-LMP) to reduce NAFLD in obese adolescents. Subjects with intra-hepatic triglyceride content (IHTC) equal to or greater than 5% diagnosed by proton-magnetic resonance spectroscopy (1H-MRS) were enroled and randomly assigned to either the D-LMP intervention or conventional paediatrician-led consultation (P-CON) group. Subjects in the P-CON group received usual care consisting of a consultation by a paediatrician with the child and parents every 16 weeks. Intention-to-treat analysis was used for data analysis. Fifty-two subjects were recruited, with 26 in each group. After the initiation phase (at week-16), there was a greater difference in the change in the IHTC and BMI z-score in the D-LMP group (P = 0.029 and |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink