Comparing the Safety and Efficacy of Microwave Ablation Using ThermosphereTM Technology versus Radiofrequency Ablation for Hepatocellular Carcinoma: A Propensity Score-Matched Analysis
Autor: | Takayoshi Oikawa, Hiroki Sato, Kei Endo, Yudai Fujiwara, Hidekatsu Kuroda, Yohei Kooka, Tamami Abe, Kei Sawara, Tomoaki Nagasawa, Yasuhiro Takikawa |
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Rok vydání: | 2021 |
Předmět: |
Cancer Research
medicine.medical_specialty Radiofrequency ablation medicine.medical_treatment lcsh:RC254-282 Article law.invention 03 medical and health sciences 0302 clinical medicine law Overall survival Medicine Single lesion business.industry Microwave ablation hepatocellular carcinoma lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Ablation Oncology microwave ablation 030220 oncology & carcinogenesis Hepatocellular carcinoma Propensity score matching 030211 gastroenterology & hepatology radiofrequency ablation Radiology business |
Zdroj: | Cancers Volume 13 Issue 6 Cancers, Vol 13, Iss 1295, p 1295 (2021) |
ISSN: | 2072-6694 |
Popis: | There is limited information regarding the oncological benefits of microwave ablation using ThermosphereTM technology for hepatocellular carcinoma. This study compared the overall survival and recurrence-free survival outcomes among patients with hepatocellular carcinoma after microwave ablation using ThermosphereTM technology and after radiofrequency ablation. Between December 2017 and August 2020, 410 patients with hepatocellular carcinoma (a single lesion that was ≤5 cm or ≤3 lesions that were ≤3 cm) underwent ablation at our institution. Propensity score matching identified 150 matched pairs of patients with well-balanced characteristics. The microwave ablation and radiofrequency ablation groups had similar overall survival rates at 1 year (99.3% vs. 98.2%) and at 2 years (88.4% vs. 87.5%) (p = 0.728), as well as similar recurrence-free survival rates at 1 year (81.1% vs. 76.2%) and at 2 years (60.5% vs. 62.1%) (p = 0.492). However, the microwave ablation group had a significantly lower mean number of total insertions (1.22 ± 0.49 vs. 1.59 ± 0.94 p < 0.0001). This retrospective study revealed no significant differences in the overall survival and recurrence-free survival outcomes after microwave ablation or radiofrequency ablation. However, we recommend microwave ablation for hepatocellular carcinoma tumors with a diameter of > 2 cm based on the lower number of insertions. |
Databáze: | OpenAIRE |
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