Independent risk factors for death in patients admitted for asthma exacerbation in Taiwan

Autor: Chia Chen Hsu, Yuh-Lih Chang, Kang-Cheng Su, Chia-Lin Chou, Tzeng Ji Chen, Hsin-Kuo Ko, Yueh Ching Chou, Diahn-Warng Perng, Kun Ta Chou, Meng-Shui Lu
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
Epidemiology
Administration
Oral
Comorbidity
Logistic regression
0302 clinical medicine
Ambulatory Care
Odds Ratio
030212 general & internal medicine
Child
Aged
80 and over
Health Services
Middle Aged
Prognosis
Hospitalization
Child
Preschool
Prednisolone
Disease Progression
Female
medicine.drug
Pulmonary and Respiratory Medicine
Adult
Risk
medicine.medical_specialty
Adolescent
Taiwan
Article
03 medical and health sciences
Young Adult
Internal medicine
Diabetes mellitus
Sepsis
Administration
Inhalation
medicine
Diabetes Mellitus
Humans
Medical prescription
Mortality
Adrenergic beta-2 Receptor Agonists
Glucocorticoids
Asthma
Aged
lcsh:RC705-779
business.industry
Public Health
Environmental and Occupational Health
Infant
Newborn
Infant
Arrhythmias
Cardiac
Odds ratio
lcsh:Diseases of the respiratory system
Pneumonia
medicine.disease
Confidence interval
Logistic Models
030228 respiratory system
Case-Control Studies
business
Zdroj: NPJ Primary Care Respiratory Medicine
npj Primary Care Respiratory Medicine, Vol 30, Iss 1, Pp 1-8 (2020)
ISSN: 2055-1010
Popis: The independent risk factors for death in patients admitted for asthma exacerbation have not been thoroughly investigated. This study aimed to investigate these independent risk factors and the relationship between mortality and the prescription patterns of anti-asthmatic medications in patients admitted for asthma exacerbation. Using a nested case–control design, we identified 267 cases (death after asthma admission) and 1035 controls (survival after asthma admission) from the Taiwan National Health Insurance Research Database (NHIRD) from 2001 to 2010. Conditional logistic regressions were used to estimate the odds ratios (ORs) with 95% confidence intervals (CIs). We identified the independent risk factors for death as the comorbidities of pneumonia (aOR 3.82, 95% CI 2.41–6.05), genitourinary disease (aOR 1.75, 95% CI 1.17–2.62), septicemia (aOR 4.26, 95% CI 2.61–6.94), diabetes mellitus (aOR 2.10, 95% CI 1.30–3.38), arrhythmia (aOR 2.00, 95% CI 1.14–3.50), and a history of asthmatic hospitalization (aOR 4.48, 95% CI 2.77–7.25). Moreover, the use of short-acting β2-agonist (SABA) and the dosage of oral corticosteroids (OCSs) >70 mg prednisolone during previous hospitalization (all p
Databáze: OpenAIRE
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