Arterial thrombosis in four patients treated with thalidomide
| Autor: | Pamela Paplham, Theresa Hahn, Asher A. Chanan-Khan, Hilary N. Roy, Koen van Besien, Sarah L Scarpace, Philip L. McCarthy, K Brown |
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| Rok vydání: | 2004 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Lymphoma Arterial Occlusive Diseases Gastroenterology Internal medicine medicine Humans Multiple myeloma Aged Aspirin business.industry Warfarin Thrombosis Hematology Middle Aged medicine.disease Surgery Non-Hodgkin's lymphoma Thalidomide Oncology Concomitant Drug Therapy Combination Female Intracranial Thrombosis business Multiple Myeloma medicine.drug |
| Zdroj: | Leukemialymphoma. 46(2) |
| ISSN: | 1042-8194 |
| Popis: | Thalidomide has been associated with venous thrombotic events, as reported in the post-marketing surveillance reports by Celgene Corporation; as well as case reports in the literature. Seven arterial thrombotic events have been reported in patients receiving thalidomide with 3 cases occurring in patients with other predisposing conditions. We report 4 additional cases of arterial thromboses in 1 lymphoma and 3 myeloma patients treated with thalidomide. The mechanism for these events is unclear; however, it is significant that 2 patients were receiving concomitant anticoagulation with aspirin and warfarin. |
| Databáze: | OpenAIRE |
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