Sensitivity and Specificity of Suspected Case Definition Used during West Africa Ebola Epidemic
| Autor: | Barbara Knust, Andrea M. McCollum, Sakoba Keita, Pepe Bilivogui, Lise D. Martel, Steven W Champaloux, Christopher H. Hsu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Male Pediatrics Epidemiology lcsh:Medicine specificity Disease medicine.disease_cause epidemic West africa Sensitivity and Specificity of Suspected Case Definition Used during West Africa Ebola Epidemic 0302 clinical medicine 030212 general & internal medicine Child Middle Aged Predictive value Infectious Diseases Child Preschool Female Microbiology (medical) Adult medicine.medical_specialty Adolescent 030106 microbiology Early detection Ebola virus disease World Health Organization Sensitivity and Specificity World health lcsh:Infectious and parasitic diseases 03 medical and health sciences Young Adult West Africa medicine Humans lcsh:RC109-216 viruses Epidemics suspected case definition Ebola virus business.industry Research lcsh:R Infant Hemorrhagic Fever Ebola sensitivity Virology zoonoses Guinea Ebola viruses business case definition |
| Zdroj: | Emerging Infectious Diseases Emerging Infectious Diseases, Vol 24, Iss 1, Pp 9-14 (2018) |
| ISSN: | 1080-6059 1080-6040 |
| Popis: | Rapid early detection and control of Ebola virus disease (EVD) is contingent on accurate case definitions. Using an epidemic surveillance dataset from Guinea, we analyzed an EVD case definition developed by the World Health Organization (WHO) and used in Guinea. We used the surveillance dataset (March-October 2014; n = 2,847 persons) to identify patients who satisfied or did not satisfy case definition criteria. Laboratory confirmation determined cases from noncases, and we calculated sensitivity, specificity and predictive values. The sensitivity of the defintion was 68.9%, and the specificity of the definition was 49.6%. The presence of epidemiologic risk factors (i.e., recent contact with a known or suspected EVD case-patient) had the highest sensitivity (74.7%), and unexplained deaths had the highest specificity (92.8%). Results for case definition analyses were statistically significant (p |
| Databáze: | OpenAIRE |
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