| Autor: |
Sarah Damanti, Enrica Bozzolo, Stefano Franchini, Claudia Frangi, Giuseppe Alvise Ramirez, Carla Pedroso, Giuseppe Di Lucca, Raffaella Scotti, Davide Valsecchi, Marta Cilla, Elena Cinel, Chiara Santini, Jacopo Castellani, Emanuela Manzo, Stefania Vadruccio, Marzia Spessot, Giovanni Borghi, Giacomo Monti, Giovanni Landoni, Patrizia Rovere-Querini, Mona-Rita Yacoub, Moreno Tresoldi |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Emergency medicine journal : EMJ. |
| ISSN: |
1472-0213 |
| Popis: |
BackgroundRespiratory infections can be complicated by acute brain failure. We assessed delirium prevalence, predictors and outcomes in COVID-19 ED patients.MethodsThis was a retrospective observational study conducted at the San Raffaele ED (Italy). Patients age >18 years attending the ED between 26 February 2020 and 30 May 2020 and who had a positive molecular nasopharyngeal swab for SARS-CoV-2 were included. The Chart-Based Delirium Identification Instrument (CHART-DEL) was used to retrospectively assess delirium. Univariable and multivariable logistic regression analyses were used to evaluate delirium predictors. Univariable binary logistic regression analyses, linear regression analyses and Cox regression analyses were used to assess the association between delirium and clinical outcomes. Age-adjusted and sex-adjusted models were then run for the significant predictors of the univariable models.ResultsAmong the 826 included patients, 123 cases (14.9%) of delirium were retrospectively detected through the CHART-DEL method. Patients with delirium were older (76.9±13.15 vs 61.3±14.27 years, pConclusionsChart review frequently identified ED delirium in patients with COVID-19. Age, dementia, epilepsy and polypharmacy were significant predictors of ED delirium. Delirium was associated with an increased in-hospital mortality and with a reduced probability of being discharged home after hospitalisation. The findings of this single-centre retrospective study require validation in future studies. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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