Dietary Intake of Cadmium, Lead and Mercury and Its Association with Bone Health in Healthy Premenopausal Women
| Autor: | Juan D. Pedrera-Zamorano, Jesus M. Lavado-Garcia, Jose M. Moran, Ignacio Aliaga, Raul Roncero-Martin, Luis M Puerto-Parejo, Olga Leal-Hernandez, Maria L. Canal-Macias |
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| Rok vydání: | 2017 |
| Předmět: |
Bone density
Health Toxicology and Mutagenesis Osteoporosis Physiology lcsh:Medicine Metal toxicity 010501 environmental sciences 01 natural sciences 0302 clinical medicine Absorptiometry Photon Bone Density Quantitative computed tomography heavy metals Ultrasonography Bone mineral Cadmium medicine.diagnostic_test food dietary intake bone health women’s health premenopause bone mineral density Female Adult Dietary Mercury Dietary Cadmium chemistry.chemical_element Dietética y nutrición 030209 endocrinology & metabolism Bone and Bones Article 03 medical and health sciences Metals Heavy medicine Humans Sistema musculoesquelético 0105 earth and related environmental sciences business.industry lcsh:R Public Health Environmental and Occupational Health Mercury medicine.disease Diet chemistry Lead Women's Health business Tomography X-Ray Computed |
| Zdroj: | E-Prints Complutense. Archivo Institucional de la UCM instname E-Prints Complutense: Archivo Institucional de la UCM Universidad Complutense de Madrid International Journal of Environmental Research and Public Health; Volume 14; Issue 12; Pages: 1437 International Journal of Environmental Research and Public Health International Journal of Environmental Research and Public Health, Vol 14, Iss 12, p 1437 (2017) |
| Popis: | The bone is one of the relevant target organs of heavy metals, and heavy metal toxicity is associated with several degenerative processes, such osteoporosis and bone mineral alterations, that could lead to fractures. We aimed to study a presumed relationship between bone density, evaluated by quantitative bone ultrasound (QUS), dual-energy X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT) and the dietary intake of cadmium, lead and mercury in healthy premenopausal women. A total of 158 healthy, non-smoking, premenopausal women were incorporated into the study. A validated food frequency questionnaire (FFQ) was administered to assess intake during the preceding seven days. The median predicted dietary cadmium intake among the 158 women studied was 25.29 μg/day (18.62–35.00) and 2.74 μg/kg body weight/week (b.w./w) (1.92–3.83). Dietary lead intake was 43.85 μg/day (35.09–51.45) and 4.82 μg/kg b.w./w (3.67–6.13). The observed dietary mercury intake was 9.55 μg/day (7.18–13.57) and 1.02 μg/kg b.w./w (0.71–1.48). Comparisons, in terms of heavy metal intake, showed no significant results after further adjusting for energy intake. No statistically significant correlations between heavy metal intake and the QUS, DXA and pQCT parameters were observed. Levels of dietary exposure of cadmium, lead and mercury were mostly within the recommendations. We did not find associations between the QUS, DXA and pQCT parameters and the dietary intake of the studied heavy metals in healthy premenopausal women. |
| Databáze: | OpenAIRE |
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