Hidradenoma Papilliferum: A Clinicopathologic Study of 264 Tumors From 261 Patients, With Emphasis on Mammary-Type Alterations
| Autor: | Ksenya V. Shelekhova, Heinz Kutzner, Bernhard Zelger, Colin J.R. Stewart, Denisa Kacerovska, Katrin Kerl, Jose A. Plaza, Dmitry V. Kazakov, Natalja Denisjuk, Vaclav Hejda, Michele Bisceglia, Dusan Danis, Michal Zamecnik, Anastasia M. Konstantinova, Emmanuella Guenova, Dominic V. Spagnolo, Michal Michal |
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| Přispěvatelé: | University of Zurich, Kazakov, Dmitry V |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Hidradenoma Biopsy Anal Canal 610 Medicine & health Dermatology Pathology and Forensic Medicine Acrospiroma Lesion 2708 Dermatology Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Intraductal papilloma medicine Humans Mammary Glands Human skin and connective tissue diseases Aged Aged 80 and over Vulvar neoplasm Vulvar Neoplasms Papillary hidradenoma medicine.diagnostic_test business.industry 10177 Dermatology Clinic General Medicine Middle Aged medicine.disease 2734 Pathology and Forensic Medicine Sweat Gland Neoplasms 030220 oncology & carcinogenesis Female sense organs Breast disease medicine.symptom business Anal Gland Neoplasms |
| DOI: | 10.5167/uzh-130109 |
| Popis: | Hidradenoma papilliferum (HP), also known as papillary hidradenoma, is the most common benign lesion of the female anogenital area derived from anogenital mammary-like glands (AGMLG). HP can be viewed conceptually as the cutaneous counterpart of mammary intraductal papilloma. The authors have studied 264 cases of HP, detailing various changes in the tumor and adjacent AGMLG, with emphasis on mammary-type alterations. In many HP, the authors noticed changes typical for benign breast lesions, such as sclerosing adenosis-like changes, usual, and atypical ductal hyperplasia. Almost in a third of cases, remnants of AGMLG adjacent to the lesion were evident, manifesting columnar changes reminiscent of those seen in breast lesions. This study shows that the histopathological changes in HP run a broad spectrum comparable with that in the mammary counterpart and benign breast disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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