Localization of the retinoid X receptor alpha gene (RXRA) to chromosome 9q34
| Autor: | Karen Woodward, Jonathan Wolfe, Ellen Solomon, D.R. Goudie, Susan Povey, K. A. Jones, Jude Fitzgibbon, Malcolm A. Ferguson-Smith |
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| Rok vydání: | 1993 |
| Předmět: |
Receptors
Retinoic Acid Molecular Sequence Data Retinoic acid Receptors Cytoplasmic and Nuclear Chromosomal translocation Dopamine beta-Hydroxylase Hybrid Cells Biology Retinoid X receptor Polymerase Chain Reaction Retinoids chemistry.chemical_compound Gene mapping Genetics medicine Animals Humans Cloning Molecular In Situ Hybridization Fluorescence Genetics (clinical) DNA Primers Base Sequence Retinoid X receptor alpha medicine.diagnostic_test Chromosome Mapping Cosmids Retinoid X receptor gamma Molecular biology Retinoid X Receptors chemistry Karyotyping Retinoid X receptor beta Chromosomes Human Pair 9 Transcription Factors Fluorescence in situ hybridization |
| Zdroj: | Annals of Human Genetics. 57:195-201 |
| ISSN: | 1469-1809 0003-4800 |
| DOI: | 10.1111/j.1469-1809.1993.tb01595.x |
| Popis: | The retinoid X receptor α is one of a number of retinoic acid receptors which are members of the steroid/thyroid hormone superfamily. Localization of RXRA was achieved using the polymerase chain reaction on a panel of somatic cell hybrids. A cosmid clone was isolated using the RXRA PCR product, and this was used to further localize the gene by fluorescence in situ hybridization to chromosome 9q34 distal to the dopamine β hydroxylase gene (DBH). This mapping position was confirmed by PCR on a panel of translocation hybrids. Copyright © 1993, Wiley Blackwell. All rights reserved |
| Databáze: | OpenAIRE |
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