Dosimetric analysis and experimental setup design for in-vivo irradiation with a Plasma Focus device
| Autor: | D.A. Bradley, Lorenzo Isolan, F. Mariotti, S.M. Jafari, Marco Sumini, Francesca Buontempo, Francesco Teodori |
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| Přispěvatelé: | Isolan, L., Sumini, M., Teodori, F., Bradley, D., Jafari, S., Mariotti, F., Buontempo, F. |
| Rok vydání: | 2019 |
| Předmět: |
Plasma Focu
Materials science Monte Carlo method Radiation In-vivo experiments 01 natural sciences In-vivo experiment Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine In vivo 0103 physical sciences Irradiation Monte Carlo Dense plasma focus 010308 nuclear & particles physics Radiation field Medical application Plasma Focus equipment and supplies Dose Medical applications Thermoluminescent dosimeter Biomedical engineering |
| Zdroj: | Radiation Physics and Chemistry. 155:17-21 |
| ISSN: | 0969-806X |
| DOI: | 10.1016/j.radphyschem.2018.06.025 |
| Popis: | Looking at possible clinical applications of the Plasma Focus (PF) technology as medium-low energy extremely fast radiation source, aiming at the treatment of skin cancer pathologies, in vivo experiments on mice are a due step. To properly design the experiments, a dosimetric analysis on a PMMA mouse phantom has been devised and carried out. The dose delivered to the phantom has been evaluated in experiments using Gafchromic films, standard TLD chips and TL glass beads to be able to optimally reconstruct the radiation field produced by the PF at various depths in the phantom. The whole setup has also been analysed with a Monte Carlo model using the MCNP6 code to produce a correlation between the results obtained from the various dosimetric technologies. |
| Databáze: | OpenAIRE |
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