Platelet mass index and prediction of severity of transient tachypnea of the newborn
| Autor: | Meltem Bor, Ozkan Ilhan |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Blood Platelets
Male medicine.medical_specialty Time Factors Transient tachypnea of the newborn 030204 cardiovascular system & hematology Sensitivity and Specificity Severity of Illness Index Tachypnea 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine medicine Humans Platelet Platelet mass Mean platelet volume Retrospective Studies Intermittent mandatory ventilation Platelet Count business.industry Transient Tachypnea of the Newborn Infant Newborn Area under the curve Gestational age medicine.disease Pediatrics Perinatology and Child Health Cardiology Female medicine.symptom business Mean Platelet Volume Biomarkers |
| Zdroj: | Pediatrics International. 61:697-705 |
| ISSN: | 1442-200X 1328-8067 |
| DOI: | 10.1111/ped.13899 |
| Popis: | Platelet mass index (PMI) is associated with platelet functionality. The aim of this study was to evaluate the role of PMI in predicting the severity of transient tachypnea of the newborn (TTN).Infants with gestational age ≥37 weeks and birthweight ≥2,000 g who were given nasal intermittent mandatory ventilation for TTN ≤6 h after birth were retrospectively enrolled in this study. PMI was calculated using the following formula: PMI = platelet count × mean platelet volume/10The PMI and platelet count were significantly lower in the group with tachypnea duration48 h than in the tachypnea duration ≤48 h group (P0.001 and P = 0.04, respectively). A negative significant correlation was noted between PMI and the duration of tachypnea (r = -0.43, P0.001). A PMI cut-off of 1,562 fL/nL can predict prolonged tachypnea (48 h) with a sensitivity of 62.5%, specificity of 68.9%, positive predictive value of 71.4%, and negative predictive value of 59.6% (area under the curve, 0.682 ± 0.053; P = 0.002).Lower PMI and lower platelet count are associated with longer duration of tachypnea in patients with TTN. |
| Databáze: | OpenAIRE |
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