Development and implementation in the Monte Carlo code PENELOPE of a new virtual source model for radiotherapy photon beams and portal image calculation
| Autor: | A Croc de Suray, Thomas Dautremer, I. Chabert, Eric Barat, T. Montagu, J.C. Garcia-Hernandez, M Benkreira, D. Lazaro, L. De Carlan, M. Agelou, S. Gempp |
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| Přispěvatelé: | Laboratoire Modélisation et Simulation de Systèmes (LM2S), Département Métrologie Instrumentation & Information (DM2I), Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Service de Radiopharmacie [Hôpital de la Timone- Hôpital Nord - APHM], Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE)- Hôpital Nord [CHU - APHM], Assistance Publique - Hôpitaux de Marseille (APHM), Laboratoire National Henri Becquerel (LNHB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Département d'instrumentation Numérique (DIN (CEA-LIST)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Laboratoire d'Intégration des Systèmes et des Technologies (LIST), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST), HOPITAL NORD MARSEILLE - APHM - SERV RADIOPHARM, Assistance Publique-Hôpitaux de Marseille (AP-HM) |
| Rok vydání: | 2016 |
| Předmět: |
Computer science
[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging medicine.medical_treatment Monte Carlo method Coordinate system [SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex] 01 natural sciences Imaging phantom Collimated light 030218 nuclear medicine & medical imaging law.invention 010104 statistics & probability 03 medical and health sciences 0302 clinical medicine law Computer graphics (images) medicine Image Processing Computer-Assisted Humans Radiology Nuclear Medicine and imaging 0101 mathematics Photon beam Radiometry [STAT.AP]Statistics [stat]/Applications [stat.AP] Photons Radiological and Ultrasound Technology Phantoms Imaging Radiotherapy Planning Computer-Assisted Bremsstrahlung Collimator Radiotherapy Dosage Models Theoretical [INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation Computational physics Radiation therapy Phase space Photon beams Particle Accelerators Monte Carlo Method |
| Zdroj: | Physics in Medicine and Biology Physics in Medicine and Biology, 2016, 61 (14), pp.5215-5252. ⟨10.1088/0031-9155/61/14/5215⟩ Physics in Medicine and Biology, IOP Publishing, 2016, 61 (14), pp.5215-5252. ⟨10.1088/0031-9155/61/14/5215⟩ |
| ISSN: | 1361-6560 0031-9155 |
| Popis: | International audience; This work aims at developing a generic virtual source model (VSM) preserving all existing correlations between variables stored in a Monte Carlo pre-computed phase space (PS) file, for dose calculation and high-resolution portal image prediction. The reference PS file was calculated using the PENELOPE code, after the flattening filter (FF) of an Elekta Synergy 6 MV photon beam. Each particle was represented in a mobile coordinate system by its radial position (r(s)) in the PS plane, its energy (E), and its polar and azimuthal angles (phi(d) and theta(d)), describing the particle deviation compared to its initial direction after bremsstrahlung, and the deviation orientation. Three sub-sources were created by sorting out particles according to their last interaction location (target, primary collimator or FF). For each sub-source, 4D correlated-histograms were built by storing E, r(s), phi(d) and theta(d) values. Five different adaptive binning schemes were studied to construct 4D histograms of the VSMs, to ensure histogram efficient handling as well as an accurate reproduction of E, r(s), phi(d) and theta(d) distribution details. The five resulting VSMs were then implemented in PENELOPE. Their accuracy was first assessed in the PS plane, by comparing E, r(s), phi(d) and theta(d) distributions with those obtained from the reference PS file. Second, dose distributions computed in water, using the VSMs and the reference PS file located below the FF, and also after collimation in both water and heterogeneous phantom, were compared using a 1.5%-0 mm and a 2%-0 mm global gamma index, respectively. Finally, portal images were calculated without and with phantoms in the beam. The model was then evaluated using a 1%-0 mm global gamma index. Performance of a mono-source VSM was also investigated and led, as with the multi-source model, to excellent results when combined with an adaptive binning scheme. |
| Databáze: | OpenAIRE |
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