Variability Analysis of HIV-1 gp120 V3 Region: IV. Distribution Functions for Intra- and Inter- Subtype Amino Acid Hamming Distances
| Autor: | Maxim V. Denisov, Alex N. Yudin, Ilya V. Yaroslavtsev, Michael Yu. Shchelkanov, Alexander A. Vedenov, A. A. Slavsky, Philip O. Tsvetkov, Nicole S. Starikov, Edward V. Karamov |
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| Rok vydání: | 1998 |
| Předmět: |
chemistry.chemical_classification
Distribution (number theory) Human immunodeficiency virus (HIV) virus diseases General Medicine Computational biology HIV Envelope Protein gp120 medicine.disease_cause Bioinformatics Peptide Fragments Hierarchical clustering Amino acid Distribution function chemistry Structural Biology Histogram medicine Humans Amino Acids Mathematical Computing Molecular Biology Hamming code Mathematics |
| Zdroj: | Journal of Biomolecular Structure and Dynamics. 15:877-885 |
| ISSN: | 1538-0254 0739-1102 |
| DOI: | 10.1080/07391102.1998.10508209 |
| Popis: | Distribution functions for intra- and inter- HIV-1 V3-loop subtypes amino acid Hamming distances were calculated (850 V3-loop sequences from the Los Alamos HIV-1 Database (1996) were used). These functions have pronounced bell-like shape. Such shapes of the histograms for HIV-1 V3 intra- and inter-subtype distriutions are discussed to confirm the applicability of different hierarchical cluster procedures for HIV-1 V3 classification. Two-mode distribution for the subtype E could sertificate that this subtype includes two thinner taxons. |
| Databáze: | OpenAIRE |
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