Guidelines for the management of hereditary colorectal cancer from the British Society of Gastroenterology (BSG)/Association of Coloproctology of Great Britain and Ireland (ACPGBI)/United Kingdom Cancer Genetics Group (UKCGG)
| Autor: | Monahan, KJ, Bradshaw, N, Dolwani, S, Desouza, B, Dunlop, MG, East, JE, Ilyas, M, Kaur, A, Lalloo, F, Latchford, A, Rutter, MD, Tomlinson, I, Thomas, HJW, Hill, J, Group, Hereditary CRC Guidelines Edelphi Consensus |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Colorectal cancer
Peutz-Jeghers Syndrome Gastroenterology DNA Glycosylases 0302 clinical medicine Risk Factors Family history Referral and Consultation education.field_of_study medicine.diagnostic_test Intestinal Polyposis Adenomatous Polyposis Coli/genetics Intestinal Polyposis/congenital Neoplastic Syndromes Hereditary/genetics Colonoscopy Lynch syndrome Referral and Consultation/standards 3. Good health Adenomatous Polyposis Coli Population Surveillance 030220 oncology & carcinogenesis surveillance 030211 gastroenterology & hepatology Colorectal Neoplasms medicine.medical_specialty Hereditary CRC guidelines eDelphi consensus group Population colorectal cancer genetic testing 03 medical and health sciences Neoplastic Syndromes Hereditary Internal medicine Colorectal Neoplasms Hereditary Nonpolyposis/genetics medicine Humans Gastrointestinal cancer Peutz-Jeghers Syndrome/genetics education Life Style Genetic testing Family Health Cancer prevention Gastroenterology & Hepatology business.industry 1103 Clinical Sciences Guideline DNA Glycosylases/genetics medicine.disease Colorectal Neoplasms/genetics Colorectal Neoplasms Hereditary Nonpolyposis inherited cancers United Kingdom 1114 Paediatrics and Reproductive Medicine colorectal surgery business Ireland |
| Zdroj: | 2019, ' Guidelines for the management of hereditary colorectal cancer from the British Society of Gastroenterology (BSG)/Association of Coloproctology of Great Britain and Ireland (ACPGBI)/United Kingdom Cancer Genetics Group (UKCGG) ', Gut, vol. 69, no. 3, pp. 411-444 . https://doi.org/10.1136/gutjnl-2019-319915, https://doi.org/10. 1136/ gutjnl-2019-319915 Monahan, KJ, Bradshaw, N, Dolwani, S, Desouza, B, Dunlop, MG, East, JE, Ilyas, M, Kaur, A, Lalloo, F, Latchford, A, Rutter, MD, Tomlinson, I, Thomas, HJW, Hill, J & group, H CRC G ED C 2019, ' Guidelines for the management of hereditary colorectal cancer from the British Society of Gastroenterology (BSG)/Association of Coloproctology of Great Britain and Ireland (ACPGBI)/United Kingdom Cancer Genetics Group (UKCGG). ', Gut . https://doi.org/10.1136/gutjnl-2019-319915 |
| Popis: | Heritable factors account for approximately 35% of colorectal cancer (CRC) risk, and almost 30% of the population in the UK have a family history of CRC. The quantification of an individual’s lifetime risk of gastrointestinal cancer may incorporate clinical and molecular data, and depends on accurate phenotypic assessment and genetic diagnosis. In turn this may facilitate targeted risk-reducing interventions, including endoscopic surveillance, preventative surgery and chemoprophylaxis, which provide opportunities for cancer prevention. This guideline is an update from the 2010 British Society of Gastroenterology/Association of Coloproctology of Great Britain and Ireland (BSG/ACPGBI) guidelines for colorectal screening and surveillance in moderate and high-risk groups; however, this guideline is concerned specifically with people who have increased lifetime risk of CRC due to hereditary factors, including those with Lynch syndrome, polyposis or a family history of CRC. On this occasion we invited the UK Cancer Genetics Group (UKCGG), a subgroup within the British Society of Genetic Medicine (BSGM), as a partner to BSG and ACPGBI in the multidisciplinary guideline development process. We also invited external review through the Delphi process by members of the public as well as the steering committees of the European Hereditary Tumour Group (EHTG) and the European Society of Gastrointestinal Endoscopy (ESGE). A systematic review of 10 189 publications was undertaken to develop 67 evidence and expert opinion-based recommendations for the management of hereditary CRC risk. Ten research recommendations are also prioritised to inform clinical management of people at hereditary CRC risk. |
| Databáze: | OpenAIRE |
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