Effect of Diagnosis on Outcomes in the Setting of Enhanced Recovery Protocols

Autor: Julia R. Berian, Jason B. Liu, Julie K. M. Thacker, Clifford Y. Ko, Liane S. Feldman, Kristen A. Ban
Rok vydání: 2018
Předmět:
Adult
Male
Reoperation
medicine.medical_specialty
Databases
Factual

medicine.medical_treatment
Administration
Oral

Inflammatory bowel disease
Patient Readmission
Perioperative Care
Diverticulitis
Colonic

Cohort Studies
03 medical and health sciences
Ileostomy
0302 clinical medicine
Postoperative Complications
Clinical Protocols
Internal medicine
medicine
Humans
Surgical Wound Infection
Mortality
Colectomy
Aged
Retrospective Studies
Analgesics
Pain
Postoperative

business.industry
Gastroenterology
Retrospective cohort study
General Medicine
Recovery of Function
Diverticulitis
Length of Stay
Middle Aged
medicine.disease
Inflammatory Bowel Diseases
Prognosis
Colorectal surgery
Elective Surgical Procedures
030220 oncology & carcinogenesis
Colonic Neoplasms
030211 gastroenterology & hepatology
Female
Elective Surgical Procedure
business
Cohort study
Zdroj: Diseases of the colon and rectum. 61(7)
ISSN: 1530-0358
Popis: BACKGROUND Implementation of enhanced recovery protocols in colectomy reduces length of stay and morbidity, but it remains unknown whether benefits vary by clinical diagnosis. OBJECTIVE Outcomes after colectomy in the setting of enhanced recovery protocols were compared for 3 diagnoses: 1) neoplasm, 2) diverticulitis, and 3) IBD. DESIGN This was a retrospective registry-based cohort study. SETTINGS Novel enhanced recovery variables were released in the American College of Surgeons National Surgical Quality Improvement Program in 2014. PATIENTS Patients with enhanced recovery variable data undergoing elective colectomy (July 2014 to December 2015) for neoplasm, diverticulitis, or IBD were included. MAIN OUTCOME MEASURES The primary outcome of interest was prolonged length of stay. Additional outcomes included surgical site infection, death/serious morbidity, reoperation, readmission, and days to achieve per os pain control, tolerance of a diet, and return of bowel function. RESULTS We identified 4620 patients with neoplasm, 1730 patients with diverticulitis, and 593 patients with IBD. Patients undergoing colectomy for IBD were more likely to have prolonged length of stay (OR, 1.98; 95% CI, 1.46-2.69), death/serious morbidity (OR, 1.62; 95% CI, 1.13-2.32), and readmission (OR, 1.54; 95% CI, 1.15-2.08) compared with patients with neoplasm. Patients with IBD took longer than patients with neoplasm or diverticulitis to achieve per os pain control (mean, 4.2 days vs 3.4 and 3.5 days, p < 0.001) and tolerate a diet (mean, 4.1 days vs 3.7 and 3.5 days, p < 0.001). No statistically significant differences in outcomes between patients with neoplasm and diverticulitis were seen. LIMITATIONS There may be heterogeneity among implemented enhanced recovery protocols. CONCLUSIONS Patients undergoing colectomy for neoplasm and diverticulitis have improved outcomes in comparison with patients undergoing colectomy for IBD. Knowledge of expected outcomes for patients with different diagnoses may inform clinician and patient expectations. See Video Abstract at http://links.lww.com/DCR/A623.
Databáze: OpenAIRE