Development of surface-enhanced Raman spectroscopy application for determination of illicit drugs: Towards a practical sensor
| Autor: | Pan Li, Meihong Ge, Qiwen Xie, Borong Yu, Liangbao Yang |
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| Rok vydání: | 2019 |
| Předmět: |
Illicit Drugs
Chemistry 010401 analytical chemistry Nanotechnology 02 engineering and technology Surface-enhanced Raman spectroscopy Spectrum Analysis Raman 021001 nanoscience & nanotechnology Molecular Fingerprint 01 natural sciences Body Fluids 0104 chemical sciences Analytical Chemistry Humans 0210 nano-technology |
| Zdroj: | Talanta. 191:1-10 |
| ISSN: | 0039-9140 |
| DOI: | 10.1016/j.talanta.2018.08.032 |
| Popis: | Surface-enhanced Raman spectroscopy (SERS) has been widely applied to identify or detect illicit drugs, because of the ability for highly specific molecular fingerprint and independence of aqueous solutions impact. We summarize the progress in determination of illicit drugs using SERS, including trace illicit drugs, suspicious objects and drugs or their metabolites in real biological system (urine, saliva and so on). Even though SERS detection of illicit drugs in real samples still remains a huge challenge because of the complex unknown environment, the efficient sample separation and the improved hand-held Raman analyzer will provide the possibility to make SERS a practically analytical technique. Moreover, we put forward a prospective overview for future perspectives of SERS as a practical sensor for illicit drugs determination. Perhaps the review is not exhaustive, we expect to help researchers to understand the evolution and challenges in this field and further interest in promoting Raman and SERS as a practical analyzer for convenient and automated illicit drugs identification. |
| Databáze: | OpenAIRE |
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