Gold Nanoparticles Displaying Tumor-Associated Self-Antigens as a Potential Vaccine for Cancer Immunotherapy
| Autor: | Eui-Cheol Shin, Sukmo Kang, Daejin Kim, Minsuk Choi, In-Hyun Lee, Sangyong Jon, Phei Er Saw, Sukyung Ahn |
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| Rok vydání: | 2014 |
| Předmět: |
Ovalbumin
medicine.medical_treatment Biomedical Engineering Metal Nanoparticles Pharmaceutical Science Cancer Vaccines Cell Line Biomaterials Interferon-gamma Mice Immune system Cancer immunotherapy Antigens Neoplasm In vivo Neoplasms Animals Medicine Cytotoxic T cell Mice Inbred BALB C biology business.industry Dendritic Cells Immunotherapy Fibronectins Fibronectin Colloidal gold Immunology biology.protein Interleukin-2 Gold Antibody business T-Lymphocytes Cytotoxic |
| Zdroj: | Advanced Healthcare Materials. 3:1194-1199 |
| ISSN: | 2192-2640 |
| DOI: | 10.1002/adhm.201300597 |
| Popis: | Golden vaccine for cancers. Gold nanoparticles enable efficient antigen delivery to dendritic cells and then activate the cells to facilitate cross-presentation, inducing antigen-specific cytotoxic T-lymphocyte responses for effective cancer therapy. |
| Databáze: | OpenAIRE |
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