Dietary flour supplementation decreases post-menopausal hot flushes: effect of soy and wheat
| Autor: | Catherine B Lombard, M.S. Morton, Gisela Wilcox, Boyd Josef Gimnicher Strauss, A.L. Murkies, Henry G. Burger |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
medicine.medical_specialty Diet therapy Flour Wheat flour Phytoestrogens General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Animal science Double-Blind Method Internal medicine Flushing Medicine Humans Estrogens Non-Steroidal Daidzin Triticum Aged business.industry fungi Daidzein food and beverages Obstetrics and Gynecology Isoflavones Middle Aged medicine.disease Urinary calcium Menopause Postmenopause Endocrinology chemistry Female Plant Preparations Soybeans business |
| Zdroj: | Maturitas. 61(1-2) |
| ISSN: | 0378-5122 |
| Popis: | Plants contain compounds with oestrogen--like action called phytoestrogens. Soy contains daidzin, a potent phytoestrogen, and wheat flour contains less potent enterolactones. We aimed to show in 58 postmenopausal women (age 54, range 30-70 years) with at least 14 hot flushes per week, that their daily diet supplemented with soy flour (n = 28) could reduce flushes compared with wheat flour (n = 30) over 12 weeks when randomised and double blind. Hot flushes significantly decreased in the soy and wheat flour groups (40% and 25% reduction, respectively < 0.001 for both) with a significant rapid response in the soy flour group in 6 weeks (P < 0.001) that continued. Menopausal symptom score decreased significantly in both groups (P < 0.05). Urinary daidzein excretion confirmed compliance. Vaginal cell maturation, plasma lipids and urinary calcium remained unchanged. Serum FSH decreased and urinary hydroxyproline increased in the wheat flour group. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect