Decreasing Non–bladder-cancer Mortality After Radical Cystectomy
| Autor: | Christian Thomas, Matthias Hübler, Angelika Borkowetz, Vladimir Novotny, Manfred P. Wirth, Ulrike Heberling, Michael Froehner, Rainer Koch |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Heart disease Life expectancy Urology medicine.medical_treatment Comorbidity Cystectomy Age Competing risk analysis Brief Correspondence medicine Mortality Patient summary Selection RC254-282 Bladder cancer business.industry Hazard ratio Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Diseases of the genitourinary system. Urology Confidence interval Radical cystectomy RC870-923 business |
| Zdroj: | European Urology Open Science European Urology Open Science, Vol 29, Iss, Pp 15-18 (2021) |
| ISSN: | 2666-1683 |
| DOI: | 10.1016/j.euros.2021.04.007 |
| Popis: | Life expectancy is increasing in many parts of the world. Using proportional hazard models for competing risks, we investigated whether this increase has changed outcomes after radical cystectomy in a sample of 1419 consecutive patients treated between 1993 and 2018. During the observation period, the mean age and the proportion of patients with American Society of Anesthesiologists physical status class 3 or 4 increased, whereas the proportion of patients with heart disease decreased. Competing mortality (causes other than bladder cancer) decreased in all subgroups (hazard ratios [HRs] per year ranged from 0.931 to 0.963) and after controlling for increasing age (HRs ranged from 1.018 to 1.081). In an optimal model resulting from an analysis including age (HR per year 1.048, 95% confidence interval [CI] 1.027–1.070; p |
| Databáze: | OpenAIRE |
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