Polypharmacy and sarcopenia in hospitalized older patients: results of the GLISTEN study
| Autor: | Agosta, Luca, Mario, Bo, Bianchi, Lara, Abete, Pasquale, Belelli, Giuseppe, Cherubini, Antonio, Corica, Francesco, Di Bari, Mauro, Maggio, Marcello, Manca, Giovanna Maria, Rizzo, Maria Rosaria, Rossi, Andrea, Landi, Francesco, Volpato, Stefano, Brombo, Gloria, Ortolani, Beatrice, Savino, Elisabetta, Maietti, Elisa, Fisichella, Alberto, Buttò, Valeria, Zamboni, Mauro, Caliari, Cesare, Ferrari, Elena, Orso, Francesco, Sacco, Flavia, Di meo, Laura, Cerri, Anna Paola, Motta, Marco, Pittella, Francesca, Bonfanti, Alessandra, Fusco, Sergio, PRESTIPINO GIARRITTA, Valeria, Soraci, Luca, Pili, Fausto Giordano, Basile, Claudia, Coppola, Carla, Dalise, Anna Maria, Fava, Ilaria, Catte, Olga, Orrù, Maura, Salaris, Paolo, Martone, Anna Maria, Ortolani, Elena, Salini, Sara, Dell’Aquila, Giuseppina, Carrier, Barbara |
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| Přispěvatelé: | Agosta, L., Bo, M., Bianchi, L., Abete, P., Belelli, G., Cherubini, A., Corica, F., Di Bari, M., Maggio, M., Manca, G. M., Rizzo, M. R., Rossi, A., Landi, F., Volpato, S., Brombo, G., Ortolani, B., Savino, E., Maietti, E., Fisichella, A., Butto, V., Zamboni, M., Caliari, C., Ferrari, E., Orso, F., Sacco, F., Dimeo, L., Cerri, A. P., Motta, M., Pittella, F., Bonfanti, A., Fusco, S., Prestipinogiarritta, V., Soraci, L., Pili, F. G., Basile, C., Coppola, C., Dalise, A. M., Fava, I., Catte, O., Orru, M., Salaris, P., Martone, A. M., Ortolani, E., Salini, S., Dell'Aquila, G., Carrier, B. |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Gerontology
Male Aging medicine.medical_specialty In-patients Sarcopenia Polypharmacy Skeletal muscle Aged Aged 80 and over Cross-Sectional Studies Female Humans Independent Living Italy Prevalence Risk Factors Geriatric Assessment Socio-culturale Geriatrics and Gerontology 03 medical and health sciences 0302 clinical medicine Older patients Acute care medicine 80 and over 030212 general & internal medicine Cross-Sectional Studie High prevalence business.industry Risk Factor musculoskeletal system medicine.disease body regions In-patient Older people business human activities 030217 neurology & neurosurgery Human |
| Popis: | Background: Recently the Berlin Aging Study II (BASE-II) showed that polypharmacy is associated with clinically relevant sarcopenia among community-dwelling older persons. Here we report findings from the GLISTEN study about the association of polypharmacy with sarcopenia among older medical in-patients. Methods: The GLISTEN study investigated prevalence and clinical correlates of sarcopenia in older patients admitted to geriatric and internal medicine acute care wards of 12 Italian hospitals. Results: In this sample of older medical in-patients with high prevalence of sarcopenia (34.7%) and polypharmacy (70.2%) we did not observe a significant association of polypharmacy with sarcopenia. Conclusions: Present findings demonstrate that the association of polypharmacy with sarcopenia, observed in the BASE-II study, is not evident in the GLISTEN sample, being our patients significantly older, more multi-morbid, with high prevalence of sarcopenia and polypharmacy, suggesting that this association might vary according to the heterogeneous health, functional, and nutritional characteristics of older people. |
| Databáze: | OpenAIRE |
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