Early neuroleptic response in psychotic men and women: Correlation with plasma HVA and MHPG

Autor: Mary E. Swigar, Malcolm B. Bowers, Frederick J. Hoffman, Nora Giocoechea, Peter Jatlow
Rok vydání: 1986
Předmět:
Zdroj: Comprehensive Psychiatry, Vol 27, Iss 3, Pp 181-185 (1986)
ISSN: 0010-440X
DOI: 10.1016/0010-440x(86)90038-6
Popis: We measured fasting free plasma HVA and MHPG prior to neuroleptic treatment in 47 psychotic inpatients. Early neuroleptic response (ten days) was significantly related to plasma homovanillic acid (HVA) in both sexes, plasma methoxyhydroxyphenylethylene glycol (MHPG) in women, and length of hospital stay in both men and women. Drug dose did not determine early response. As a group, women were more depressed on admission, received lower neuroleptic doses, and were discharged sooner than men. Plasma catecholamine metabolites deserve further study as correlates of neuroleptic treatment in psychotic disorders.
Databáze: OpenAIRE