Clinical and haemodynamic variables associated with intensive care unit length of stay and early adverse outcomes after the Norwood procedure
| Autor: | Helena Staehler, Masamichi Ono, Patrick Schober, Takashi Kido, Paul Philipp Heinisch, Martina Strbad, Janez Vodiskar, Julie Cleuziou, Julia Lemmer, Gunter Balling, Alfred Hager, Peter Ewert, Jürgen Hörer |
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| Přispěvatelé: | Anesthesiology, ACS - Microcirculation, APH - Methodology, APH - Quality of Care |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Pulmonary and Respiratory Medicine
Hemodynamics Infant Newborn General Medicine Length of Stay Norwood Procedures Heart Septal Defects Atrial Intensive Care Units Treatment Outcome Risk Factors Hypoplastic Left Heart Syndrome Lactates Birth Weight Humans Surgery Cardiology and Cardiovascular Medicine Retrospective Studies |
| Zdroj: | Staehler, H, Ono, M, Schober, P, Kido, T, Heinisch, P P, Strbad, M, Vodiskar, J, Cleuziou, J, Lemmer, J, Balling, G, Hager, A, Ewert, P & Hörer, J R 2022, ' Clinical and haemodynamic variables associated with intensive care unit length of stay and early adverse outcomes after the Norwood procedure ', European Journal of Cardio-thoracic Surgery, vol. 61, no. 6, pp. 1271-1280 . https://doi.org/10.1093/ejcts/ezac014 European Journal of Cardio-thoracic Surgery, 61(6), 1271-1280. Elsevier |
| ISSN: | 1010-7940 |
| DOI: | 10.1093/ejcts/ezac014 |
| Popis: | OBJECTIVES This study was performed to determine the clinical and haemodynamic variables associated with early adverse outcomes after the neonatal Norwood procedure. METHODS Patients who underwent the neonatal Norwood procedure between 2001 and 2019 were included. The patient diagnosis, morphological characteristics and haemodynamic parameters were analysed to identify factors associated with length of stay (LOS) in the intensive care unit (ICU) and mortality during the stay. RESULTS A total of 322 patients were depicted. The median age and weight at the Norwood procedure were 9 days and 3.2 kg, respectively. Certain morphological and preoperative parameters, such as birth weight below 2.5 kg, restrictive atrial septal defect, extracardiac anomalies and the diameter of the ascending aorta, were found to be associated with the LOS in the ICU. Analysis using early postoperative haemodynamic variables revealed that systolic arterial pressure, diastolic arterial pressure, serum lactate levels and reduced ventricular function at 2 days postoperatively were associated with the LOS in the ICU. Birth weight CONCLUSIONS The LOS in the ICU after the Norwood procedure was predicted by early postoperative haemodynamic variables, suggesting that good early postoperative haemodynamics determine early recovery. A prolonged stay in the ICU after the Norwood procedure was associated with late mortality. |
| Databáze: | OpenAIRE |
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