Impact of orocecal transit time on patient's perception of lactose intolerance
| Autor: | Juan R. Malagelada, Maite Casaus, Francesc Casellas, Anna Aparici, P. Rodríguez |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Gerontology medicine.medical_specialty Time Factors Transit time Gastroenterology Lactose malabsorption Diagnostic Self Evaluation chemistry.chemical_compound Hydrogen breath test Lactose Intolerance Surveys and Questionnaires Internal medicine medicine Humans Self perceived In patient Orocecal transit time Lactose Gastrointestinal Transit Cecum Breath test Lactase activity Mouth Lactose intolerance medicine.diagnostic_test business.industry General Medicine medicine.disease Breath Tests chemistry Patient s perception Female business |
| Zdroj: | Revista Española de Enfermedades Digestivas v.105 n.1 2013 SciELO España. Revistas Científicas Españolas de Ciencias de la Salud instname |
| ISSN: | 1130-0108 |
| DOI: | 10.4321/s1130-01082013000100004 |
| Popis: | Background: symptoms attributed to the lactose intolerance are an important public health issue because of their prevalence and social relevance. Also because they may cause undue rejection of dairy products consume with potential health consequences. Transit time is a putative factor implied in the severity of symptoms asso ciated with lactose. Objectives: to elucidate the relation between orocecal transit time (OCTT) and lactose intolerance symptoms. Methods: observational study in patients referred to a lactose hydrogen breath test who showed an increase in breath H 2 excretion higher than 25 ppm. OCTT was measured with the breath test and symptoms of lactose tolerance with a validated scale. Symptoms were measured twice: before receiving the lactose, inquiring about self perceived symptoms when patients consumed dairy products at home (“home symptoms”), and again after completing the lactose breath test (“test symptoms”). Results: 161 patients were included. There was no correlation between OCTT and home symptoms (r = -0.1). When OCTT was faster than 60 minutes, intensity of “test symptoms” was similar to “home symptoms”. However, in patients with normal or slow OCTT, the “home symptoms” were more intense than the “test symptoms” (p < 0.05). At home, symptoms were independent of OCTT but with the lactose test load the symptoms were proportionately more intense with faster OCTT. Conclusions: in lactose maldigesters, selfreported symptoms of lactose intolerance are more pronounced at home than after a high lactose challenge. Intolerance symptoms that patients attributed to lactose consume at home are due to factors other than fast OCTT. |
| Databáze: | OpenAIRE |
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