Human adenovirus-36 seropositivity and obesity among Midwestern US adolescents
| Autor: | Mollie G Wasserman, Matthew T. McLeay, Aneesh K Tosh, Sara Tepe |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
biology business.industry Public Health Environmental and Occupational Health Elisa assay Control subjects medicine.disease Obesity 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine Pediatrics Perinatology and Child Health medicine biology.protein Obese group 030212 general & internal medicine Sample collection Antibody Risk factor business Body mass index |
| Zdroj: | International Journal of Adolescent Medicine and Health. 32 |
| ISSN: | 2191-0278 0334-0139 |
| DOI: | 10.1515/ijamh-2017-0126 |
| Popis: | Objective Human adenovirus-36 (Ad-36) infection has been implicated as a risk factor for obesity. This study aims to measure Ad-36 antibody prevalence among obese and healthy-weight Midwestern US adolescents. Methods Obese and healthy-weight subjects 10–18 years of age attending an adolescent clinic in Missouri, USA, were tested for Ad-36 antibodies via ELISA assay. All subjects were measured for height and weight to determine body mass index (BMI). χ2 analysis was used to compare Ad-36 antibody prevalence between the two groups. Results Ad-36 antibodies were tested on 41 obese and 37 control subjects. The subjects’ mean age at the time of sample collection was 15.6 years (SD 2.0). Ad-36 antibody prevalence was 43.9% among the obese group and 21.6% among the control group (p = 0.038). Discussion The findings show that statistically more obese Missouri adolescents test positive for Ad-36 antibodies than their healthy-weight peers, consistent with previous findings suggesting a correlation between Ad-36 infection and obesity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|