In vitro antimicrobial susceptibility of Mycoplasma mycoides mycoides large colony and Arcanobacterium pyogenes isolated from clinical cases of ulcerative balanitis and vulvitis in Dorper sheep in South Africa
| Autor: | M. Van Vuuren, Bruce Gummow, Johan Gouws, A. Kidanemariam |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
Male
Florfenicol Colony Count Microbial Sheep Diseases Arcanobacterium Pyogenes Microbial Sensitivity Tests Oxytetracycline Biology Vulvitis Arcanobacterium pyogenes Microbiology chemistry.chemical_compound Balanitis Drug Resistance Bacterial medicine Enrofloxacin Animals Corynebacterium pyogenes Tilmicosin Sheep lcsh:Veterinary medicine Dose-Response Relationship Drug General Veterinary Broth microdilution Spiramycin Mycoplasma mycoides General Medicine biochemical phenomena metabolism and nutrition biology.organism_classification Minimum Inhibitory Concentrations Anti-Bacterial Agents Mycoplasma Mycoides Mycoides Ulcerative Balanoposthitis And Vulvovaginitis Dorper Sheep Treatment Outcome chemistry lcsh:SF600-1100 Female medicine.drug |
| Zdroj: | Journal of the South African Veterinary Association, Vol 76, Iss 4, Pp 204-208 (2005) Scopus-Elsevier |
| ISSN: | 2224-9435 1019-9128 |
| Popis: | The in vitro activities of enrofloxacin, florfenicol, oxytetracycline and spiramycin were determined against field isolates of Mycoplasma mycoides mycoides large colony (MmmLC) by means of the broth microdilution technique. The minimum inhibitory concentrations (MICs) of these antimicrobial drugs were determined for a representative number of 10 isolates and 1 type strain. The susceptibility of Arcanobacterium pyogenes to enrofloxacin, oxytetracycline and tilmicosin was determined by means of an agar disk diffusion test. The MICs of enrofloxacin, florfenicol, oxytetracycline and spiramycin were within the ranges of 0.125-0.5, 1.0-2.0, 2.0-4.0 and 4.0-8.0 µg / m , respectively. This study has shown that resistance of MmmLC against enrofloxacin, florfenicol, oxytetracycline and spiramycin was negligible. All the field strains of A. pyogenes that were tested were susceptible to enrofloxacin, oxytetracycline and tilmicosin with mean inhibition zones of 30.6, 42.3 and 35.8mm, respectively. Although there is lack of data on in vivo efficacy and in vitro MIC or inhibition zone diameter breakpoints of these antimicrobial drugs for MmmLC, the MIC results indicate that these 4 classes of antimicrobial drugs should be effective in the treatment of ulcerative balanitis and vulvitis in sheep in South Africa. |
| Databáze: | OpenAIRE |
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