A Dosimetric Comparison between Conventional and Conformal Technique of Chest Wall Radiation in Breast Cancer Patients - A Single Institute Cross Sectional Study at Basavatarakam IndoAmerican Cancer Hospital and Research Institute

Autor: Akkineni Naga Prasanthi, Aparna Suryadevara, Yakub Mohmd
Rok vydání: 2021
Předmět:
Zdroj: Journal of Evidence Based Medicine and Healthcare, Vol 8, Iss 18, Pp 1252-1257 (2021)
ISSN: 2349-2570
2349-2562
DOI: 10.18410/jebmh/2021/240
Popis: BACKGROUND Breast cancer is the most common cancer among Indian women and adjuvant radiation is an integral part of its management. Adjuvant radiation can be planned by 2D conventional or conformal technique. The most common technique has been 2D technique worldwide, especially in high volume, low resource settings. The comparison of 2D and conformal techniques for chest wall and lymph nodal areas among breast cancer patients is sparse in the literature. The purpose of our study was to dosimetrically compare the 2 D conventional and field-in-field intensity modulating radiational therapy (FiF IMRT) technique in adjuvant radiation to chest wall + / - SCF / axilla areas at Basavatarakam Indo-American Cancer Hospital and Research Institute. METHODS This is a single institute cross sectional study. During immobilisation for planning and CT scan, external radio-opaque markers were placed over chest wall. After contouring and planning by FiF IMRT technique, 2D conventional plan was done by placing MT, LT fields + / - SCF by SSD technique with the guidance of the markers placed and both plans were compared by the dose-volume histogram (DVH) analysis. RESULTS The planning target volume (PTV) coverage was lower with the 2D plan but the advantage of the 2D plan was, it showed lower OAR compared to FiF IMRT plan. The studies comparing PTV coverage and OAR doses between 2D and conformal techniques were mostly done in BCS patients and similar studies for chest wall radiation are rare in the literature and with conflicting results and different methods of 2D planning with modification of 2D plans than what is done routinely. Our study used the 2D plan by SSD technique and also manual MU calculation without normalisation of the plan to the contoured PTV, unlike other studies to minimise the deviation in 2D plan and hence, the comparison of the PTV or OAR doses with FiF IMRT plans. CONCLUSIONS The 2D plan for chest wall planned by tangential fields has the disadvantage in being less homogenous and conformal but with much lower OAR doses than FiF IMRT. It is a safe to treat as far as OARs are considered. KEYWORDS Conventional, Conformal, FIF IMRT, Comparison, Chest Wall Radiation, Breast Cancer
Databáze: OpenAIRE