Unusual dermoscopic patterns of basal cell carcinoma mimicking melanoma
| Autor: | Eleonora Di Matteo, Riccardo Pampena, Maria A. Pizzichetta, Elisa Cinotti, Johanna Chester, Shaniko Kaleci, Marco Manfredini, Stefania Guida, Emi Dika, Elvira Moscarella, Aimilios Lallas, Zoe Apalla, Giuseppe Argenziano, Jian L Perrot, Linda Tognetti, Michela Lai, Carmen Cantisani, Vincenzo Roberti, Diletta Fiorani, Carlotta Baraldi, Leonardo Veneziano, Chryssoula Papageorgiou, Silvana Ciardo, Pietro Rubegni, Iris Zalaudek, Annalisa Patrizi, Caterina Longo, Luca Bianchi, Giovanni Pellacani, Francesca Farnetani |
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| Přispěvatelé: | Di Matteo, E., Pampena, R., Pizzichetta, M. A., Cinotti, E., Chester, J., Kaleci, S., Manfredini, M., Guida, S., Dika, E., Moscarella, E., Lallas, A., Apalla, Z., Argenziano, G., Perrot, J. L., Tognetti, L., Lai, M., Cantisani, C., Roberti, V., Fiorani, D., Baraldi, C., Veneziano, L., Papageorgiou, C., Ciardo, S., Rubegni, P., Zalaudek, I., Patrizi, A., Longo, C., Bianchi, L., Pellacani, G., Farnetani, F., Di Matteo E., Pampena R., Pizzichetta M.A., Cinotti E., Chester J., Kaleci S., Manfredini M., Guida S., Dika E., Moscarella E., Lallas A., Apalla Z., Argenziano G., Perrot J.L., Tognetti L., Lai M., Cantisani C., Roberti V., Fiorani D., Baraldi C., Veneziano L., Papageorgiou C., Ciardo S., Rubegni P., Zalaudek I., Patrizi A., Longo C., Bianchi L., Pellacani G., Farnetani F. |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Skin Neoplasms
malignant melanoma basal cell carcinoma dermoscopy non-invasive diagnosis non-invasive techniques Dermatology Biochemistry Sensitivity and Specificity Diagnosis Differential Settore MED/35 Carcinoma Basal Cell Humans non-invasive diagnosi Molecular Biology Melanoma Retrospective Studies |
| Popis: | Background: Basal cell carcinoma can simulate melanoma and specific dermoscopic criteria have not yet been defined in a large cohort. Objective: To identify dermoscopic “trump” characteristics for differential diagnosis, identify cluster groups and assess the clinical impact of this study's findings. Methods: Retrospective, multicentric comparative study of atypical, non-facial basal cell carcinoma (≥1seven-point checklist criteria) and melanoma (with at least one BCC criteria) at dermoscopy. Observed dermoscopic features were used to develop a proposed score. Lesion clusters were defined with hierarchical analysis. Clinical impact was assessed with a blinded reader study following this study's results. Results: A total of 146 basal cell carcinoma and 76melanoma were included. Atypical vascular pattern was common to most lesions (74.5%). Twelve trump features were included in the proposed score (sensitivity 94.1% and specificity 79.5%). Cluster analysis identified 3 basal cell carcinoma and 3melanoma clusters. Findings improved overall diagnostic accuracy and confidence (26.8% and 13.8%, respectively; p |
| Databáze: | OpenAIRE |
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