Echocardiographic left ventricular geometry profiles for prediction of stroke, coronary heart disease and all-cause mortality in the Chinese community: a rural cohort population study

Autor: Zhao Li, Yingxian Sun, Xiaofan Guo, Tan Li, Guangxiao Li
Rok vydání: 2021
Předmět:
Male
Left ventricular geometry
Coronary Disease
Rural Health
030204 cardiovascular system & hematology
Ventricular Function
Left
0302 clinical medicine
Risk Factors
Cause of Death
Prospective Studies
030212 general & internal medicine
Prospective cohort study
Stroke
education.field_of_study
Ventricular Remodeling
Incidence
Hazard ratio
General population
Middle Aged
Prognosis
Cardiovascular disease
Echocardiography
Doppler
Echocardiography
Cohort
Cardiology
Female
Hypertrophy
Left Ventricular
Cardiology and Cardiovascular Medicine
Adult
China
medicine.medical_specialty
Population
Concentric hypertrophy
Risk Assessment
03 medical and health sciences
Sex Factors
Predictive Value of Tests
Internal medicine
medicine
Humans
Diseases of the circulatory (Cardiovascular) system
cardiovascular diseases
Mortality
education
Aged
Angiology
Proportional hazards model
business.industry
Research
medicine.disease
RC666-701
business
Zdroj: BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-10 (2021)
ISSN: 1471-2261
Popis: Background The utility of echocardiographic left ventricular (LV) geometry in the prediction of stroke/coronary heart disease (CHD) and all-cause mortality is not well characterized. This study aimed to evaluate the overall and sex-specific prognostic value of different geometric patterns on the incidence of stroke/CHD and all-cause mortality in a Chinese population-based cohort. Methods We conducted a prospective study in the general population in Northeast China, and a total of 9940 participants aged ≥ 35 years underwent echocardiography for LV geometry and were successfully followed up for incident stroke/CHD and all-cause death. Cox proportional hazards models were utilized to estimate the association of baseline LV geometry with adverse outcomes. Results Over a median follow-up of 4.66 years, abnormal LV geometric patterns had increased crude incident rates of stroke/CHD and all-cause mortality compared with normal geometry in overall population and each sex group (all P P Conclusions Our prospective cohort supports that abnormal LV geometry by echocardiography has a prognostic significance for incident stroke/CHD and all-cause mortality, implying that early detection and intervention of LV structural remodeling in rural China are urgently needed to prevent adverse outcomes.
Databáze: OpenAIRE
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