Echocardiographic left ventricular geometry profiles for prediction of stroke, coronary heart disease and all-cause mortality in the Chinese community: a rural cohort population study
Autor: | Zhao Li, Yingxian Sun, Xiaofan Guo, Tan Li, Guangxiao Li |
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Rok vydání: | 2021 |
Předmět: |
Male
Left ventricular geometry Coronary Disease Rural Health 030204 cardiovascular system & hematology Ventricular Function Left 0302 clinical medicine Risk Factors Cause of Death Prospective Studies 030212 general & internal medicine Prospective cohort study Stroke education.field_of_study Ventricular Remodeling Incidence Hazard ratio General population Middle Aged Prognosis Cardiovascular disease Echocardiography Doppler Echocardiography Cohort Cardiology Female Hypertrophy Left Ventricular Cardiology and Cardiovascular Medicine Adult China medicine.medical_specialty Population Concentric hypertrophy Risk Assessment 03 medical and health sciences Sex Factors Predictive Value of Tests Internal medicine medicine Humans Diseases of the circulatory (Cardiovascular) system cardiovascular diseases Mortality education Aged Angiology Proportional hazards model business.industry Research medicine.disease RC666-701 business |
Zdroj: | BMC Cardiovascular Disorders BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-10 (2021) |
ISSN: | 1471-2261 |
Popis: | Background The utility of echocardiographic left ventricular (LV) geometry in the prediction of stroke/coronary heart disease (CHD) and all-cause mortality is not well characterized. This study aimed to evaluate the overall and sex-specific prognostic value of different geometric patterns on the incidence of stroke/CHD and all-cause mortality in a Chinese population-based cohort. Methods We conducted a prospective study in the general population in Northeast China, and a total of 9940 participants aged ≥ 35 years underwent echocardiography for LV geometry and were successfully followed up for incident stroke/CHD and all-cause death. Cox proportional hazards models were utilized to estimate the association of baseline LV geometry with adverse outcomes. Results Over a median follow-up of 4.66 years, abnormal LV geometric patterns had increased crude incident rates of stroke/CHD and all-cause mortality compared with normal geometry in overall population and each sex group (all P P Conclusions Our prospective cohort supports that abnormal LV geometry by echocardiography has a prognostic significance for incident stroke/CHD and all-cause mortality, implying that early detection and intervention of LV structural remodeling in rural China are urgently needed to prevent adverse outcomes. |
Databáze: | OpenAIRE |
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