Assessment of pre-treatment cognitive performance in adult bone marrow or haematopoietic stem cell transplantation patients: A comparative study
| Autor: | Rene M.Y. Barge, Wil M.H. Eijkenboom, Jan J. Cornelissen, Arthur R. Van Gool, Martin J. van den Bent, Helena Harder, Hugo J. Duivenvoorden |
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| Přispěvatelé: | Neurology, Psychiatry, Hematology, Radiotherapy |
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Adolescent Neuropsychological Tests Quality of life Internal medicine medicine Humans Effects of sleep deprivation on cognitive performance Fatigue Aged Bone Marrow Transplantation Psychomotor learning medicine.diagnostic_test business.industry Hematopoietic Stem Cell Transplantation Cognition Neuropsychological test Middle Aged Surgery Transplantation medicine.anatomical_structure Oncology Hematologic Neoplasms Quality of Life Anxiety Female Bone marrow medicine.symptom Cognition Disorders business |
| Zdroj: | European Journal of Cancer, 41(7), 1007-1016. Elsevier Ltd. |
| ISSN: | 0959-8049 |
| Popis: | The aim of this study was to examine cognitive performance in patients prior to bone marrow or haematopoietic stem cell transplantation (SCT) and in haematological patients who received non-myeloablative cancer therapies. A consecutive sample of 101 SCT patients and 82 haematological patients completed a neuropsychological test battery and five questionnaires assessing subjective cognitive complaints, psychological functioning, health-related quality of life and fatigue. Results were compared with normative data. Percentages of cognitively impaired patients were equally divided between groups. Most deficits were observed in visual memory, visuospatial and constructional ability and psychomotor functions. The SCT group showed a higher rate of anxiety cases and reported lower cognitive, emotional and social functioning. Results of neuropschychological testing were not associated with outcome of the questionnaires. This study showed impaired cognitive performance prior to SCT. Haematological patients treated with non-myeloablative cancer therapies proved to be a reliable reference group for longitudinal studies. |
| Databáze: | OpenAIRE |
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