Brain-heart communication: Evidence for 'central pacemaker' oscillations with a dominant frequency at 0.1Hz in the cingulum
| Autor: | Christoph Stefan Aigner, Andreas Schwerdtfeger, Annemarie Seither-Preisler, Joana Brito, Gert Pfurtscheller, Clemens Brunner, Marciano P. Carmo, Alexandre Andrade |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Time delays Periodicity Heart rate interval Gyrus Cinguli 050105 experimental psychology 03 medical and health sciences Neural activity Electrocardiography Young Adult 0302 clinical medicine Rhythm Biological Clocks Heart Rate Physiology (medical) Cingulum (brain) Heart rate variability Humans 0501 psychology and cognitive sciences Brain Mapping Resting state fMRI 05 social sciences Electroencephalography Dominant frequency Sensory Systems Neurology Female Neurology (clinical) Psychology Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 128(1) |
| ISSN: | 1872-8952 |
| Popis: | Objectives In the brain and heart, oscillations at about 0.1 Hz are conspicuous. It is therefore worthwhile to study the interaction between intrinsic BOLD oscillations (0.1 Hz) and slow oscillations in heart rate interval (RRI) signals and differentiate between their neural and vascular origin. Methods We studied the phase-coupling with a 3T scanner with high scanning rate between BOLD signals in 22 regions and simultaneously recorded RRI oscillations in 23 individuals in two resting states. Results By applying a hierarchical cluster analysis, it was possible to separate two clusters of phase-coupling between slow BOLD and RRI oscillations in the midcingulum, one representative for neural and the other for vascular BOLD oscillations. About half of the participants revealed positive time delays characteristic for neural BOLD oscillations and neurally-driven RRI oscillations. Conclusions The results suggest that slow vascular and neural BOLD oscillations can be differentiated and that intrinsic oscillations (0.1 Hz) originate in the cingulum or its close vicinity and contribute to heart rate variability (HRV). Significance The study provides new insights into the dynamics of resting state activities, helps to explain HRV, and offers the possibility to investigate slow rhythmic neural activity changes in different brain regions without EEG recording. |
| Databáze: | OpenAIRE |
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