Reversible photo-control over transmembrane anion transport using visible-light responsive supramolecular carriers

Autor:	Matthew J. Langton, Aidan Kerckhoffs
Rok vydání:	2020
Předmět:	genetic structures Chemistry Supramolecular chemistry technology industry and agriculture General Chemistry macromolecular substances Transmembrane protein Ion Membrane Membrane protein Biophysics Lipid bilayer Anion binding Ion transporter Visible spectrum
Zdroj:	Chemical Science
ISSN:	2041-6520
Popis:	Supramolecular anion carriers responsive to visible light enable reversible two-colour photo-control over transmembrane anion transport. Ion transport across lipid bilayer membranes in biology is controlled by membrane proteins, which in turn are regulated in response to chemical-, physical- and photo-stimuli. The design of synthetic supramolecular ion transporters able to be precisely controlled by external signals, in particular bio-compatible wavelengths of visible light, is key for achieving spatio-temporal control over function. Here we report two-colour responsive molecular photo-switches that act as supramolecular transmembrane anion carriers. Reversible switching of the photo-switch within the lipid bilayer membrane is achieved using biocompatible visible wavelengths of light, such that temporal control over transmembrane anion transport is achieved through alternating irradiation with red and blue light.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac4e28424a11b00745eb8c8989181d9 https://pubmed.ncbi.nlm.nih.gov/32953027 Zobrazit plný text záznamu