Toxics source reduction and sewage upgrades eliminated winter flounder liver neoplasia (1984-2017) from Boston Harbor, MA, USA
| Autor: | Mark Lambert, Ann E. Pembroke, Kenneth Keay, Michael J. Moore, Eric C. Nestler, Maurice Hall, Lisa Lefkovitz |
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| Rok vydání: | 2018 |
| Předmět: |
0106 biological sciences
Sewage Flounder 010501 environmental sciences Aquatic Science Biology 01 natural sciences Pseudopleuronectes Animals Effluent Ecology Evolution Behavior and Systematics 0105 earth and related environmental sciences business.industry 010604 marine biology & hydrobiology Outfall Liver Neoplasms biology.organism_classification Liver Source reduction Environmental chemistry Winter flounder Sewage treatment business Water Pollutants Chemical Boston |
| Zdroj: | Diseases of aquatic organisms. 131(3) |
| ISSN: | 0177-5103 |
| Popis: | Chemical carcinogen biomarkers can validate public investment in environmental remediation. A major factor driving the clean-up of Boston Harbor, MA, USA, induced by the federal Clean Water Act legislation of 1972, was the high prevalence of petroleum and halogenated aromatic hydrocarbon contaminant-associated liver neoplasia in winter flounder Pseudopleuronectes americanus in the harbor in the 1980s. In the present study, we examined the spatial and temporal relationships between the suspended solids and contaminants in the municipal sewage discharge, and liver neoplasia and histopathology in flounder, from 1987 to 2017. Toxics source reduction, sewage treatment, and sludge removal in the 1990s and outfall relocation offshore in 2000 enabled a decreasing prevalence of persistent toxic chemicals in flounder, effluent, and sediment, and consequent disappearance of liver neoplasia and reduction of neoplasm-associated, hydropically vacuolated biliary epithelial cells to background levels. This supports long-term investment in elimination and treatment of anthropogenic waste streams and the value of federal regulatory mandates to maintain and improve regional environmental quality. |
| Databáze: | OpenAIRE |
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