A New Method to Predict the Epidemiology of Fungal Keratitis by Monitoring the Sales Distribution of Antifungal Eye Drops in Brazil
Autor: | Glauco Dreyer Viana de Carvalho, Acacio Souza Lima, Rafael Estevão de Angelis, Leonardo Tannus Malki, Marlon Moraes Ibrahim, Fuad Moraes Ibrahim, Wellington P. Martins, Marina de Paula Bichuete, Eduardo Rocha |
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Rok vydání: | 2012 |
Předmět: |
Atmospheric Science
Antifungal Agents Epidemiology medicine.medical_treatment Antifungal drug lcsh:Medicine Distribution (economics) Plant Science Toxicology 0302 clinical medicine Fungal keratitis lcsh:Science 2. Zero hunger 0303 health sciences Multidisciplinary Incidence (epidemiology) 3. Good health Infectious Diseases Medicine Seasons Public Health Eye Infections Fungal Brazil Research Article Antifungal Drugs and Devices medicine.medical_specialty medicine.drug_class Mycology Microbiology Keratitis 03 medical and health sciences medicine Humans Biology Population Biology 030306 microbiology business.industry lcsh:R Botany Eye drop medicine.disease Ophthalmology Earth Sciences 030221 ophthalmology & optometry lcsh:Q Ophthalmic Solutions business EPIDEMIOLOGIA |
Zdroj: | PLoS ONE PLoS ONE, Vol 7, Iss 3, p e33775 (2012) Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
ISSN: | 1932-6203 |
Popis: | Purpose Fungi are a major cause of keratitis, although few medications are licensed for their treatment. The aim of this study is to observe the variation in commercialisation of antifungal eye drops, and to predict the seasonal distribution of fungal keratitis in Brazil. Methods Data from a retrospective study of antifungal eye drops sales from the only pharmaceutical ophthalmologic laboratory, authorized to dispense them in Brazil (Opthalmos) were gathered. These data were correlated with geographic and seasonal distribution of fungal keratitis in Brazil between July 2002 and June 2008. Results A total of 26,087 antifungal eye drop units were sold, with a mean of 2.3 per patient. There was significant variation in antifungal sales during the year (p |
Databáze: | OpenAIRE |
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