The effects of transdermal contraception on lipid profiles, carbohydrate metabolism and coagulogram in Thai women

Autor:	Orawan Kiriwat, Somsin Petyim
Rok vydání:	2010
Předmět:	Adult Blood Glucose medicine.medical_specialty Endocrinology Diabetes and Metabolism Carbohydrate metabolism Administration Cutaneous chemistry.chemical_compound Endocrinology Internal medicine medicine Contraceptive Agents Female Humans Aspartate Aminotransferases Prospective Studies Blood Coagulation Triglycerides medicine.diagnostic_test Triglyceride business.industry Cholesterol Obstetrics and Gynecology Alanine Transaminase Fasting Thailand Lipids Lipoproteins LDL chemistry Alkaline phosphatase Carbohydrate Metabolism lipids (amino acids peptides and proteins) Thai women Female Lipid profile business Liver function tests Lipoproteins HDL Contraceptive patch medicine.drug
Zdroj:	Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 26(5)
ISSN:	1473-0766
Popis:	To evaluate the effects of the contraceptive patch on lipid profiles, carbohydrate metabolism and coagulogram in Thai women.Fifty healthy Thai women were assigned to use contraceptive patches. Blood chemistries test including liver function test, lipid profiles and coagulogram were evaluated at baseline, cycles 3 and 6.Total cholesterol, triglyceride and HDL were significantly increased, whereas LDL was slightly decreased. The ratio of total cholesterol/HDL and LDL/HDL significantly decreased when applying the patch. After discontinued use of contraceptive patch, the women whose blood tests present hypercholesterol during patch use showed a continuous decrease in blood results of total cholesterol level over 3 months. Moreover, mean fasting glucose, SGOT, SGPT and alkaline phosphate were decreased. No woman suffering from VTE in this study.The use of contraceptive patch does not exert a negative effect on carbohydrate metabolism, lipid profile, liver function test and blood coagulogram. However, further studies are required to elucidate the effect of the contraceptive on the patch user in long term.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa155244d945a7ad6a9edaa67baf4bf https://pubmed.ncbi.nlm.nih.gov/20050766 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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