Twenty-year cardiovascular and all-cause mortality trends and changes in cardiovascular risk factors in Gubbio, Italy: the role of blood pressure changes
| Autor: | Martino Laurenzi, Gianfranco Botta, Alberto Zanchetti, Oscar Terradura-Vagnarelli, Mario Mancini, Alessandro Menotti, Massimo Cirillo, Patrizia Scavizzi, Mario Angeletti, Mariapaola Lanti, Walter Panarelli |
|---|---|
| Přispěvatelé: | Menotti, A, Lanti, M, Angeletti, M, Botta, G, Cirillo, Massimo, Laurenzi, M, Mancini, M, Panarelli, W, Scavizzi, P, TERRADURA VAGNARELLI, O, Zanchetti, A. |
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Physiology Population Blood Pressure Young Adult Risk Factors Epidemiology Internal Medicine medicine Humans Risk factor education Aged education.field_of_study business.industry Middle Aged Surgery Blood pressure Italy Cardiovascular Diseases Cohort Population study Female Observational study Cardiology and Cardiovascular Medicine business Body mass index Follow-Up Studies Demography |
| Zdroj: | Journal of Hypertension. 27:266-274 |
| ISSN: | 0263-6352 |
| DOI: | 10.1097/hjh.0b013e32831cbb0b |
| Popis: | Aims In an observational population study that lasted 20 years, the relationships between mortality trends and changes in cardiovascular risk factor levels were examined. Methods and results In the town of Gubbio, in central Italy, population surveys for measurement of cardiovascular risk factors were performed 20 years apart. In a subset of the initial cohort (1927 men and 2333 women), mortality data were collected for 20 years. Cardiovascular risk factor levels were compared in individuals in the same age range (20–79 years) examined at the initial survey (1927 men and 2333 women) and at the final survey (1761 men and 2055 women). Age-adjusted rates significantly declined, by 28% among men and 51% among women, for all causes of death, and by 50% among men and 71% among women for cardiovascular disease deaths. Declines were observed in the levels of systolic blood pressure, serum cholesterol, resting heart rate, smoking habits, BMI, plasma glucose (the latter two only in women) and the estimated cardiovascular risk, together with increases in serum high-density lipoprotein cholesterol and in the proportion of treated and controlled hypertensive patients. Conclusion Although similar but less impressive changes were recorded in Italy at large, the existence of the observational study in Gubbio might have motivated the general population and the medical profession towards actions promoting general health. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|