The relationship between body mass index and mortality in patients with acute decompensated heart failure

Autor: Andrew J. Burger, Doron Aronson, Yuchi Han
Rok vydání: 2009
Předmět:
Zdroj: International Journal of Cardiology. 134:132-135
ISSN: 0167-5273
DOI: 10.1016/j.ijcard.2007.12.047
Popis: Recent studies have suggested that body mass index (BMI) may be an independent prognostic factor in patients with chronic heart failure (HF). It is unknown whether or not BMI has the same predictive value in acute decompensated heart failure. We studied 489 patients with the previous diagnosis of HF (84% NYHA class III-IV) who were admitted for decompensated HF. During follow-up of greater than 6 months, 110 patients (22.4%) died. Kaplan-Meier analysis demonstrated that patients with BMI25 kg/m(2) were at a higher risk of death. After adjusting for other risk variables in a Cox proportional hazard regression model, BMI25 kg/m(2) remained an independent predictor of mortality with a hazard ratio of 1.6 (95% CI 1.1-2.4, p=0.03). We conclude that BMI in the normal or cachectic range is an independent predictor of mortality in patients with acute decompensated HF.
Databáze: OpenAIRE