Ultrasound bone mass in schizophrenic patients on antipsychotic therapy
| Autor: | Jesus M. Lavado-Garcia, Purificacion Rey-Sanchez, Raul Roncero-Martin, Juan D. Pedrera-Zamorano, M.A. Gómez-Zubeldia, Maria L. Canal-Macias |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Acid Phosphatase Urology Parathyroid hormone Bone remodeling Finger Phalanges Sex Factors Bone Density Internal medicine medicine Vitamin D and neurology Humans Pharmacology (medical) Vitamin D Antipsychotic Metre per second Aged Ultrasonography Tartrate-resistant acid phosphatase Tartrate-Resistant Acid Phosphatase business.industry Ultrasound Middle Aged Alkaline Phosphatase Prolactin Isoenzymes Psychiatry and Mental health Endocrinology Neurology Parathyroid Hormone Schizophrenia Female Controlled Clinical Trials as Topic Neurology (clinical) business Antipsychotic Agents |
| Zdroj: | Human Psychopharmacology: Clinical and Experimental. 24:49-54 |
| ISSN: | 1099-1077 0885-6222 |
| DOI: | 10.1002/hup.984 |
| Popis: | Objective To determine bone mass using quantitative phalangeal bone ultrasound in institutionalized schizophrenic patients under chronic treatment with antipsychotic drugs. Methods A total of 73 patients with schizophrenia (25 women, mean age 59.84 � 17.01 years; 48 men, mean age 61.89 � 12.95 years) and 73 healthy subjects (25 women, mean age 60.37 � 17.16 years; 48 men, mean age 61.24 � 13.09 years) participated in the study. Bone status was assessed using an ultrasound device that measures the amplitude-dependent speed of sound (Ad-SoS) in metres per second. Measurements were made on the phalanges (II‐V) of the non-dominant hand, and the mean value was computed. Results The schizophrenic women had higher levels of prolactin (PRL), parathyroid hormone (PTH), alkaline phosphatase (AlPh), and tartrate-resistant acid phosphatase (TRAP) (all p |
| Databáze: | OpenAIRE |
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