Prevalence of hepatitis B virus infection and associated risk factors among pregnant women attending antenatal clinic in Mulago Hospital, Uganda: a cross-sectional study
| Autor: | Simon Peter Kayondo, Peter Ntuyo, Josaphat Byamugisha |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Mulago Hospital Blood transfusion Referral Cross-sectional study medicine.medical_treatment 030231 tropical medicine prevalence medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Pregnancy Obstetrics and Gynaecology Medicine Humans Uganda 030212 general & internal medicine Pregnancy Complications Infectious Hepatitis B virus business.industry Obstetrics Prenatal Care General Medicine Hepatitis B medicine.disease 3. Good health Cross-Sectional Studies Marital status Observational study Female business pregnant women Social status |
| Zdroj: | BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | AimTo determine the prevalence and factors associated with hepatitis B virus infection among pregnant women attending antenatal clinic in Mulago Hospital.DesignCross-sectional observational study.SettingMulago National Referral Hospital, Uganda, antenatal clinic.ParticipantsWe randomly selected 340 pregnant women attending their first antenatal visit at Mulago Hospital antenatal clinic.Primary outcomeHepatitis B surface antigen positivity.ResultsWe recruited 340 participants, with a mean age of 27±5.7 years, and a median gravidity of 3. The prevalence of hepatitis B virus infection among pregnant women attending the antenatal clinic in Mulago Hospital, in our study, was 2.9% (95% CI 1.58% to 5.40%, n=10). Factors positively associated with hepatitis B virus infection were: marital status (adjusted OR (aOR)=11.37, p=0.002), having a hepatitis B positive family member (aOR=49.52, pConclusionThe prevalence of hepatitis B virus infection among pregnant women attending antenatal clinic in Mulago Hospital was of intermediate endemicity. We found that marital status, having a hepatitis B positive family member at home and having had a blood or body fluid splash to mucous membranes from a hepatitis B positive patient were independently associated with hepatitis B infection. Factors such as age, HIV status, history of blood transfusion, piercing of ears and social status were not associated with hepatitis B status in this study. |
| Databáze: | OpenAIRE |
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