| Autor: |
Biren Khimji Patel, Anand Binu, Antony Stanley, Shrey Kumar Shah, Darshan H.R., Tobin George, Easwer H.V., Prakash Nair |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
World Neurosurgery. 167:e694-e704 |
| ISSN: |
1878-8750 |
| DOI: |
10.1016/j.wneu.2022.08.070 |
| Popis: |
Large pituitary adenomas (LPAs), which constitute ∼5%-14% of all pituitary adenomas, are considered challenging tumors owing to their locally aggressive behavior, low gross total resection rate, and high prevalence of visual deficits and hypopituitarism. We evaluated the utility of various extended endoscopic endonasal approaches in maximizing the resection of LPAs and studied the factors affecting the extent of surgical resection.A retrospective study of all LPAs (defined as a minimum diameter3 cm and tumor volume10 cmThe present study included 106 patients with LPAs. The mean extent of the resection volume was 79.18 ± 21.75 cmExtended endoscopic endonasal approaches can safely and effectively be used for gross total resection of LPAs. However, we found that the preoperative tumor volume and Knosp grade were significant factors affecting the extent of tumor resection. The use of multiple endoscopic endonasal corridors can increase the volumetric extent of resection for LPAs. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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