Determinants of Incomplete Left Ventricular Mass Regression Following Aortic Valve Replacement for Aortic Stenosis
| Autor: | Christopher D. Morgan, Stephen E. Fremes, Hari R. Mallidi, Campbell D. Joyner, Vivek Rao, Gideon Cohen, George T. Christakis, Bernard S. Goldman, Naoji Hanayama |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Hemodynamics Left ventricular hypertrophy Logistic regression Muscle hypertrophy Aortic valve replacement Risk Factors Internal medicine medicine Humans Prospective Studies Prospective cohort study Aged Ultrasonography Heart Valve Prosthesis Implantation business.industry Aortic Valve Stenosis Odds ratio medicine.disease Stenosis Treatment Outcome Heart Valve Prosthesis Disease Progression Cardiology Female Hypertrophy Left Ventricular Surgery Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Cardiac Surgery. 20:307-313 |
| ISSN: | 1540-8191 0886-0440 |
| DOI: | 10.1111/j.1540-8191.2005.200485.x |
| Popis: | OBJECTIVE Incomplete regression of left ventricular hypertrophy (Abn-LVMI) following AVR for aortic stenosis (AS) may decrease long-term survival. In this prospective study, we identified the predictors of Abn-LVMI. METHODS Between 1990 and 2000, 529 patients undergoing AVR for AS had clinical and hemodynamic data collected prospectively. Preoperative and annual postoperative transthoracic echos were employed to assess left ventricular mass index (LVMI) and hemodynamics. Abn-LVMI was defined as the 75th percentile of the lowest postoperative LVMI (>128 mg/m2, n = 133). All other patients were included in the normal regression group (N-LVMI). Univariate and multivariable logistic regression analyses were used to determine the predictors of Abn-LVMI. RESULTS Preoperative hypertension, diabetes, coronary disease, valve size, mean postoperative gradients, effective orifice area, and patient-prosthesis mismatch (PPM, indexed EOA |
| Databáze: | OpenAIRE |
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