Successful treatment of a humeral capitulum osteonecrosis with bone morphogenetic protein-7 combined with autologous bone grafting

Autor:	Nils P. Hailer, Richard Marsell
Rok vydání:	2014
Předmět:	Adult medicine.medical_specialty Percutaneous Bone Morphogenetic Protein 7 Radiography Elbow Case Report from Uppsala University Hospital Bone morphogenetic protein Lesion bone morphogenetic protein osteochondritis dissecans medicine Humans Bone graft Humerus Bone Transplantation business.industry osteonecrosis elbow General Medicine medicine.disease Combined Modality Therapy Osteochondritis dissecans Surgery Bone morphogenetic protein 7 medicine.anatomical_structure Female medicine.symptom business
Zdroj:	Upsala Journal of Medical Sciences
ISSN:	2000-1967 0300-9734
Popis:	We present the case of a 27-year-old female with subcortical osteonecrosis of the humeral capitulum. Percutaneous retrograde drilling of the lesion and application of recombinant human bone morphogenetic protein (BMP)-7 were combined with autologous bone grafting. At follow-up the patient was almost pain-free, had normalized her range of motion, and radiography showed consolidation of the lesion without any heterotopic bone formation. By timing surgery prior to subchondral collapse, biomechanical stability of the subchondral bone was maintained. To our knowledge, this is the first report on the treatment of an osteonecrosis in this location with a BMP, and this strategy could potentially be applied in other locations with juxta-articular osteonecrosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497fe824395a12d0e3c8a79fcbef3253 https://doi.org/10.3109/03009734.2014.931493 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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