Perceptions of Patients with Primary Nonadherence to Statin Medications

Autor: Derjung M. Tarn, Jon A. Turner, Alicia Fernandez, Keith Cox, Maureen Barrientos, Mark J. Pletcher, Janice B. Schwartz
Rok vydání: 2021
Předmět:
Adult
medicine.medical_specialty
Statin
medicine.drug_class
media_common.quotation_subject
Hypercholesterolemia
Hyperlipidemias
Disease
030204 cardiovascular system & hematology
Cardiovascular
Article
Medication Adherence
03 medical and health sciences
0302 clinical medicine
7.1 Individual care needs
Clinical Research
General & Internal Medicine
Perception
medicine
Humans
cardiovascular diseases
030212 general & internal medicine
Adverse effect
Qualitative Research
media_common
Pharmaceutical industry
business.industry
Prevention
Statins
Public Health
Environmental and Occupational Health

Evaluation of treatments and therapeutic interventions
nutritional and metabolic diseases
Focus Groups
Health Services
Focus group
Heart Disease
Good Health and Well Being
Cardiovascular Diseases
6.1 Pharmaceuticals
Family medicine
Public Health and Health Services
lipids (amino acids
peptides
and proteins)

Management of diseases and conditions
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Worry
Family Practice
business
Qualitative research
Zdroj: J Am Board Fam Med
Journal of the American Board of Family Medicine : JABFM, vol 34, iss 1
ISSN: 1558-7118
1557-2625
Popis: Background: Despite emphasis on efforts to prevent cardiovascular disease (CVD), 13% to 34% of people never fill a prescribed statin (primary nonadherence). This study determined perceptions of adults with primary nonadherence to statins. Methods: Ten focus groups were conducted with 61 adults reporting primary nonadherence to statins (93% without known CVD). Participants were recruited from an academic medical center and nationwide Internet advertisements. Results: Major themes related to primary nonadherence were 1) desire to pursue alternatives before starting a statin (eg, diet and/or exercise, dietary supplements), 2) worry about risks and adverse effects of statins, 3) perceptions of good personal health (suggesting that a statin was not needed), and 4) doubt about the benefits of statins in the absence of disease. Additional themes included mistrust of the pharmaceutical industry, mistrust of prescribing providers, inadequate provider communication about statins, and negative prior experiences with medication. Although rare, a few patients said that high cholesterol does not require treatment if it is genetic. One third noted during focus group discussions that they did not communicate their decision not to take a statin to providers. Conclusions: Adults with primary nonadherence to statins describe seeking alternatives, avoiding perceived risks of statins, poor acceptance/understanding of CVD risk estimates, and doubts about the benefits of statins. Many do not disclose their decisions to providers, thus highlighting the need for provider awareness of the potential for primary nonadherence at the point of prescribing, and the need for future work to develop strategies to identify patients with potential primary nonadherence.
Databáze: OpenAIRE