Sensors
| Autor: | Sangwoo Oh, Dongmin Seo, Sungkyu Seo, Sung-Ho Paek, Se-Hwan Paek |
|---|---|
| Přispěvatelé: | Biological Systems Engineering |
| Rok vydání: | 2016 |
| Předmět: |
Bio-layer interferometry
Hospital setting 030209 endocrinology & metabolism Enzyme free continuous glucose monitoring competitive assay glucose dialysismethod bio-layer interferometry needle-type sensor Interference (wave propagation) lcsh:Chemical technology 01 natural sciences Biochemistry Analytical Chemistry 03 medical and health sciences 0302 clinical medicine Medicine lcsh:TP1-1185 Electrical and Electronic Engineering Instrumentation Glycemic Reproducibility business.industry Continuous glucose monitoring Communication 010401 analytical chemistry Needle type Atomic and Molecular Physics and Optics 0104 chemical sciences business glucose dialysis method Biomedical engineering |
| Zdroj: | Sensors (Basel, Switzerland) Sensors, Vol 16, Iss 10, p 1581 (2016) SENSORS(16): 10 |
| ISSN: | 1424-8220 |
| Popis: | The incidence of diabetes is continually increasing, and by 2030, it is expected to have increased by 69% and 20% in underdeveloped and developed countries, respectively. Therefore, glucose sensors are likely to remain in high demand in medical device markets. For the current study, we developed a needle-type bio-layer interference (BLI) sensor that can continuously monitor glucose levels. Using dialysis procedures, we were able to obtain hypoglycemic samples from commercial human serum. These dialysis-derived samples, alongside samples of normal human serum were used to evaluate the utility of the sensor for the detection of the clinical interest range of glucose concentrations (70–200 mg/dL), revealing high system performance for a wide glycemic state range (45–500 mg/dL). Reversibility and reproducibility were also tested over a range of time spans. Combined with existing BLI system technology, this sensor holds great promise for use as a wearable online continuous glucose monitoring system for patients in a hospital setting. Published version |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|