Can the tea tree oil (Australian native plant:Melaleuca alternifolia Cheel) be an alternative treatment for human demodicosis on skin?
| Autor: | Robert C Griffin, Mu-Kai Chen, James C.G. Doery, Nelson Siukei Lam, Xin Xin Long |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Mite Infestations
Population Biology 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Tea Tree Oil Demodex brevis parasitic diseases Mite medicine Demodicosis Animals Humans education Skin Mites education.field_of_study Traditional medicine Terpenes Terpinen-4-ol Melaleuca alternifolia Tea tree oil Melaleuca biology.organism_classification medicine.disease Infectious Diseases chemistry 030221 ophthalmology & optometry Animal Science and Zoology Parasitology Demodex medicine.drug |
| Zdroj: | Parasitology. 145:1510-1520 |
| ISSN: | 1469-8161 0031-1820 |
| DOI: | 10.1017/s0031182018000495 |
| Popis: | Australian tea tree oil (TTO) and its extract terpinen-4-ol (T4O) are found to be effective in moderating demodex-related diseases. Their possible effects are lowering the mite counts, relieving the demodex-related symptoms and modulating the immune system especially the inflammatory response. This review summarizes the topical treatments of TTO and T4O in human demodicosis, their possible mechanism of actions, side-effects and potential resistance in treating this condition. Although current treatments other than TTO and T4O are relatively effective in controlling the demodex mite population and the related symptoms, more research on the efficacy and drug delivery technology is needed in order to assess its potential as an alternative treatment with minimal side-effect profile, low toxicity and low risk of demodex resistance. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|