The long-term predictive value of the neutrophil-to-lymphocyte ratio in Type 2 diabetic patients presenting with acute myocardial infarction
| Autor: | L.-C. Lee, Kian Keong Poh, Swee Guan Teo, Boon-Lock Chia, Glenn K Lee, Eric Chong, Chi-Hang Lee |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Neutrophils Myocardial Infarction Comorbidity Risk Assessment Cohort Studies Leukocyte Count Internal medicine Diabetes mellitus medicine Humans Lymphocyte Count Lymphocytes Myocardial infarction Neutrophil to lymphocyte ratio Aged medicine.diagnostic_test business.industry Incidence (epidemiology) fungi Hazard ratio Complete blood count General Medicine Middle Aged Prognosis medicine.disease Survival Analysis Surgery Causality Diabetes Mellitus Type 2 Quartile Acute Disease Cohort Cardiology Female business |
| Zdroj: | QJM. 105:1075-1082 |
| ISSN: | 1460-2393 1460-2725 |
| DOI: | 10.1093/qjmed/hcs123 |
| Popis: | Background: Patients with diabetes mellitus have worse long-term outcomes after acute myocardial infarction (AMI) than non-diabetics. This may be related to differential contribution of neutrophil and lymphocyte to inflammation during AMI in diabetics vs. non-diabetics. We aim to determine the predictive value of neutrophil-to-lymphocyte ratio (NLR) for major adverse events post-AMI in Type 2 diabetics vs. non-diabetics. Methods and Results: A total of 2559 consecutive patients admitted for AMI (61 ± 14 years, 73% male and 43% diabetic) were analyzed. A complete blood count was obtained and the NLR computed for each patient on admission. Across the cohort, the 1-year reinfarction rate was 8.4% ( n = 214) and 1-year mortality was 14.5% ( n = 370). Univariate determinants of the composite endpoint included age, hypertension, hyperlipidemia, smoking, revascularization and NLR ( P |
| Databáze: | OpenAIRE |
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