Seborrheic Keratosis With Prominent Clear Cell Changes—A Rare But Important Diagnostic Variant
| Autor: | Thomas H. Long, David Zlotnick, Stanley L. Hurst, Zsolt B. Argenyi |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
Seborrheic keratosis medicine.medical_specialty Glycogen accumulation Keratosis Seborrheic keratoses Dermatology Pathology and Forensic Medicine Lesion 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Biopsy medicine Humans Keratosis Seborrheic medicine.diagnostic_test Left shoulder business.industry General Medicine Middle Aged medicine.disease 030220 oncology & carcinogenesis medicine.symptom business Clear cell |
| Zdroj: | The American Journal of Dermatopathology. 40:209-211 |
| ISSN: | 0193-1091 |
| DOI: | 10.1097/dad.0000000000000992 |
| Popis: | Seborrheic keratoses, although exceedingly common, occasionally have morphologic similarities to other lesions that complicate a typically straightforward diagnosis. The authors present a case of a 69-year-old man with a left shoulder lesion that displayed characteristic clinical and microscopic features of seborrheic keratosis on biopsy. However, diffuse and prominent clear cells were also noted. These stained strongly with Periodic acid-Schiff and were diastase sensitive, suggestive of glycogen accumulation and possible trichilemmal differentiation. This case is presented to demonstrate a unique and striking example of clear cell change within a seborrheic keratosis and to briefly review the published literature on this finding, which is rarely reported and demands close examination to exclude more aggressive neoplasms. |
| Databáze: | OpenAIRE |
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