Prostate interventions in patients with mild haemophilia: Safe and feasible
| Autor: | Gabriella Hakim, B. Mesnard, Julien Branchereau, I. Chelghaf, Nicolas Drillaud, Arthur David, Jérôme Rigaud, Marc Trossaert, Marc Fouassier, Marianne Sigaud, Samuel Chelly, Marie-Aimée Perrouin Verbe, Catherine Ternisien, Stéphane De Vergie |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Prostate biopsy medicine.medical_treatment Haemophilia A Population Prostatic Hyperplasia Hemophilia A Haemophilia Prostate medicine Humans Haemophilia B education Genetics (clinical) education.field_of_study medicine.diagnostic_test business.industry Prostatectomy Transurethral Resection of Prostate Hematology General Medicine medicine.disease Surgery Treatment Outcome medicine.anatomical_structure Prostate surgery business |
| Zdroj: | Haemophilia. 27 |
| ISSN: | 1365-2516 1351-8216 |
| Popis: | Introduction To date, there is no specific recommendation or evaluation of the morbidity of prostate surgery in patients with haemophilia (PWH) although this surgery is common and at high risk of bleeding. Aim To assess the post-operative morbidity of benign prostate hyperplasia (BPH) surgeries and of oncological prostate interventions in patients with mild haemophilia A or B. Methods We performed a monocentre, epidemiological, in real life study. Data were collected between 1 January, 1997 and 1 September, 2020 and focused on prostate biopsy, radical prostatectomy, prostate radiotherapy, simple prostatectomy, transurethral resection of prostate (TURP) and laser-vaporisation in patients with mild haemophilia A or B. Results Between 1 January, 1997 and 1 September, 2020, 51 interventions were performed on 30 patients with mild haemophilia. Haemophilia A represented 93.33% of the population and haemophilia B 6.67%. For prostate biopsies (n = 24), median length of hospitalisation was 4 days and only one patient needed a blood transfusion. No patient needed re-admission. For prostatectomy (n = 10), one patient presented with intra-operative and post-operative bleeding. Two patients required re-admission. The other patients did not present any significant haemorrhagic symptoms. For radiotherapy (n = 4), two patients presented a grade II complication (radiocystitis and radiorectitis). For BPH surgeries, during hospitalisation, laser-vaporisation (n = 5) was less haemorrhagic than TURP (n = 5) but after hospital discharge, 60% of patients presented a haemorrhagic complication with two readmissions and one surgical re-explorations. Conclusion Performed in a specialised centre, prostate surgeries and interventions in patients with mild haemophilia is feasible with acceptable morbidity. |
| Databáze: | OpenAIRE |
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