Bactericidal Action of Streptomycin
| Autor: | Geoffrey Rake, Richard Donovick, Dorothy Hamre |
|---|---|
| Rok vydání: | 1946 |
| Předmět: |
biology
medicine.drug_class Chemistry Gram-positive bacteria Antibiotics Bacillus sp Bactericidal effect biology.organism_classification General Biochemistry Genetics and Molecular Biology Anti-Bacterial Agents Spore Microbiology Streptomycin medicine Incubation Beta lactam antibiotics medicine.drug |
| Zdroj: | Experimental Biology and Medicine. 62:25-31 |
| ISSN: | 1535-3699 1535-3702 |
| Popis: | SummaryStreptomycin was bactericidal for both multiplying and non—multiplying cultures of K. pneumoniae, but not for washed spores of Bacillus sp. No. 290. Organisms surviving the bactericidal effect of 0.25 unit of streptomycin per ml after 6 hours incubation were more resistant to its action. This resis—tance persisted through 4 subcultures in the ab-sence of streptomycin and could be increased 5-fold by serial transfers in broth containing streptomycin. Washed organisms surviving after 5 hours incubation with 7.5 units of streptomycin per ml were not more resistant. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|