Pancreatic duct secretion: experimental methods, ion transport mechanisms and regulation
| Autor: | J. San Román, José Julián Calvo, P. Hernández-Lorenzo, Mónica García |
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| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Physiology Cell Culture Techniques Paracrine Communication Ion Pumps Punctures Biology Biochemistry Gastrointestinal Hormones Paracrine signalling Secretin Internal medicine Peripheral Nervous System medicine Animals Humans Endocrine system Secretion Pancreatic duct Ion Transport Cell Membrane Pancreatic Ducts General Medicine Pancreas Exocrine Cell biology Perfusion medicine.anatomical_structure Endocrinology Pancreatic juice Duodenum Pancreas |
| Zdroj: | Journal of Physiology and Biochemistry. 64:243-257 |
| ISSN: | 1877-8755 1138-7548 |
| DOI: | 10.1007/bf03178846 |
| Popis: | The pancreatic ductal tree conveys enzymatic acinar products to the duodenum and secretes the fluid and ionic components of pancreatic juice. The physiology of pancreatic duct cells has been widely studied, but many questions are still unanswered concerning their mechanisms of ionic transport. Differences in the transport mechanisms operating in the ductal epithelium has been described both among different species and in the different regions of the ductal tree. In this review we summarize the methods developed to study pancreatic duct secretion both in vivo and in vitro, the different mechanisms of ionic transport that have been reported to date in the basolateral and luminal membranes of pancreatic ductal cells and the regulation of pancreatic duct secretion by nervous, endocrine and paracrine influences. |
| Databáze: | OpenAIRE |
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