Thrombotic risk in patients undergoing peripheral stem cell apheresis and low-molecular weight heparin prophylaxis pre-apheresis
| Autor: | Francesco Picardi, Durazzi Sm, Politi P |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.drug_class Low molecular weight heparin Gastroenterology Young Adult Risk Factors Internal medicine medicine Autologous transplantation Humans Platelet Young adult Aged business.industry Incidence (epidemiology) Thrombosis Hematology Heparin Low-Molecular-Weight Middle Aged medicine.disease Surgery Apheresis Blood Component Removal Female Stem cell business |
| Zdroj: | Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 47(2) |
| ISSN: | 1473-0502 |
| Popis: | Patients undergoing peripheral blood stem cell (PBSC) collection for autologous transplantation may have a greater incidence of thrombosis due to a number of risk factors (RFs). These factors may be related to the patient himself (history of thromboembolism, tumour type and stage, treatment), to the procedure and/or to the mobilizing agents used. In our study of 97 patients, 32 were considered high risk (HR) patients and were therefore treated with a low prophylactic dose of enoxaparin the evening before stem cell apheresis. Neither thrombotic nor hemorrhagic complications were observed, even though pre-apheresis platelet levels were below 50×10(9)l(-1) in 19 procedures. |
| Databáze: | OpenAIRE |
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